脂肪肝在成人健康檢查中,是腹部超音波檢查常見的異常之一,有些受檢者僅是脂肪肝,有些則合併肝臟生化異常。為了解脂肪肝與肝生化異常的相關性,我們回溯林口長庚醫院家庭醫院家庭醫學科,自2001年1月到12月在北台灣多家工廠所做的常規性腹部超音波檢查。總共有1,061位健檢勞工接受腹部超音波檢查,有641位(佔60.4%)發現有魯肪肝,其中290位(佔45.2%)合併有肝生化異常。除了B型肝炎、C型肝炎以及酒精性等可能造成肝生化異常的因子外,我們探討可能造成脂肪肝肝生化異常的相關因子。結果發現,有脂肪肝且同時有肝生化異常的民眾,其主要相關因子為男性,三酸甘油酯,以及肥胖。較有趣的是,酒精是造成脂肪肝的一個重要成因,但卻不是脂肪肝病患合併肝生化異常的重要影響因子。
Fatty liver is one of the most common pictures of the abdominal ultrasonographic survey in the health checkup of Chinese laborers. Some subjects are of abnormal liver biochemistry. In order to disclose the association between fatty liver and abnormal liver biochemistry, we retrospectively analyzed the factory laborers who received abdominal sonographic studies during their health checkups, from January to December 2001. All of the 1,061 laborers who were recruited, 641 were found to have fatty liver in this study. Aside from the potential factors of abnormality of liver biochemistry such as hepatitis B, hepatitis C and alcohol abuse, we examined other possible factors. The revealed that man, hyperlipidemia and obesity are highly associated with abnormal liver biochemistry. Interestingly, alcohol is the cause of fatty liver in this study, but it doesn’t increase the risk of abnormal liver biochemistry.