Ectopic thyroid tissue located in the submandibular region was rather rare and that with a coexisting normal locate thyroid gland had been reported in only two papers. In March 2000, we had a patient who suffered from right submandibular mass for two years. She ever received thyroid surgery for nodular goiter of left lobe of thyroid 6 years ago at other hospital. Cytology of fine needle aspiration showed inflammation cells. After excision of the tumor, the final pathology diagnosis was nodular goiter. The patient recovered well after the surgery and had no complications or signs of hypothyroidism after one year of follow up.