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如意金黃散與接骨散在骨折癒合過程中的病理研究

Effects of Ru-Yih-Jin-Huang-Saan (RYJHS) and Jie-Guu-Saan (JGS) on the Healing of Experimental Fracyure in an Animal Model

摘要


本研究的目的是觀察外敷如意金黃散與口服接骨散在促進骨折癒合過程中的生化影響。將大白鼠的左脛腓骨中段,用定點手法,造成閉合性骨折,隨機分為對照組,林格氏液組,外敷如意金黃散組,內服接骨散組及外敷如意金黃散與內服接骨散組。定4天、8天、12天三個觀察點,觀察骨折癒合過程中的各種變化。

並列摘要


The purpose of this study was to observe the biochemical and pathological effects of ru-yih-jin-huang-saan (RYJHS) and jin-guu-saan (JGS) on experimental fracture healing of the rat. Seventy-five rats were fractured in the middle of left tibia and fibula by the standard manual method. They were divided randomly into experimental and control group. They were intraperitoneally injected with Ringer's solution, used RYJHS externally or fed with FGS respectively. The animals were executed at 4, 8, and 12 days after fracture. The results demonstrated that the experimental groups were earlier and more thorough than the vontrol group, especially in the combined group of RTJHS and JGS, in the collagen formation, bone cell metabolism, enzyme system, x-ray and pathological studies.

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