Ankle sprain, frequently seen in the clinic, which diagnosis should be re-evaluate if the disease is getting worse and out of expectation. If being diagnosed as ”Minimal-dislocation”, treated with corresponding manipulation, it might facilitate the recovery. Familiar with the ”Minimal-dislocation” rules: ”1. agree with it, 2. learn from the teachers, 3. compare with the other side, 4. repeated screening test.” will elevate the manipulation success opportunity. Besides, doing best to correct the ”Minimal-dislocation” might improve the recovery, even if not really corrected to the original position.