There were three cases of ankle sprain injury. By a correct diagnosis, ankle subluxation, they could cured with a manual therapy. It is important that people can move to everywhere for living. The movement of human beings is depended on support of bone、conduction of nerve、stretch of tendon and supply of blood. The structure of human body is a precise organism which is balanced on every part. If human body suffered from functional or structural damage, it would rely on doctor to recover vitality.