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Prostaglandin E1 Versus Papaverine for Diagnosis of Erectile Dysfunction

前列腺素E1和罌粟鹼在診斷陽萎的比較

摘要


對50位勃起功能失常的病人,我們做同一位病人陰莖海綿體內,前列腺素E1和甖粟鹼的注射來比較診斷陽萎的功效。我們以不同劑量做隔週注射,觀察病人陰莖勃起的反應,並記錄注射後的所有副作用。結果顯示,20mcg前列腺素E1所引起的勃起要比60mg罌粟鹼的反應要好;而前列腺素E1的反應和劑量成正比,注射後立即引起的副作用,在二者之間並沒什麼差異,98%病人都能忍受少許的注射疼痛,至於注射後引發的過長時間勃起這種不方便,甖粟鹼則有較高(8%)的危險;基於這種考慮,臨床上前前列腺素E1應該是較安全的診斷用藥。

關鍵字

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並列摘要


In 50patients with erectile dysfunction, a comparative study with intracarvernous injection of prostaglandin E1 (PGE1) and papaverine was perfourmed. Erections with prostaglandin E1 (20 mcg) were equal or superior to those with papaverine (60 mg) in each cases. Dose-dependent effect of PGE1 was also remarkable. There was no difference of the immediate side effect between the two agents. Most of the injection pain was tolerable. Concerning the late side effect as prolong erection, PGE1 injection had less incidence than that of papaverine. Our study suggested that PGE1 was a potentially better alterantive for the diagnosis of erectile dysfunction. (J Urol R.O.C., 1: 92-96, 1990)

並列關鍵字

prostaglandin E1 papaverine impotence

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