單側椎骨動脈壓迫對耳蝸血流的影響

Effect of Unilateral Vertebral Artery Compression on Cochlear Blood Flow

譚慶鼎(Ching-Ting Tan) ； 林凱南(Kai-Nan Lin) ； 許權振(Chuan-Jen Hsu)

《中華民國耳鼻喉科醫學會雜誌》 27卷4期 (1992/12) Pp. 283-287

https://doi.org/10.6286/1992.27.4.283

摘要

椎骨動脈循環不良是造成內耳功能異常的原因之一。本研究之目的為解明單側椎骨動脈壓迫對兩側耳蝸血流的影響。吾人以15隻天竺鼠為實驗對象，自左側第3頸椎的橫突鑿孔塞入人造棉花 (cottonoid) 以壓迫椎骨動脈，然後打開胸腔，以非放射性微小球注入左心室，之後以耳蝸及血液中所含之微小球數計算兩側耳蝸之血流量。結果左側耳蝸之血流量為4.4±2.48μL/min，而右側耳蝸之血流量為3.4±1.75μL/min。此項結果顯示壓迫椎骨動脈對於對側耳蝸循環之影響遠大於同側。

關鍵字

椎骨動脈 ； 耳蝸血流量 ； 微小球

並列摘要

Streamlined blood flow pattern has been noted in the basilar artery. This may explain the fact that compromised vertebral arterial circulation will affect the function of the ipsilateral inner ear, brain stem, or cerebellum. The purpose of this study is to investigate the cochlear blood flow in the guinea pig in which one side vertebral artery is compressed. This study included 15 guinea pigs weighing 250-300g. Through ventral approach, a burr-hole was made through the left transverse process of the 3rd cervical vertebra and cottonoid pledgets were inserted for compression to the vertebral artery. Then via thoracotomy, non-radioactive microspheres were injected into the left ventricle of the heart.
Through surface preparation of the cochlea and counting of microspheres in either the cochlea and reference blood, the cochlear blood flow of each side was calculated. The results showed that the cochlear blood flow of the compressed side was larger than the non-compressed side. We concluded that the unilateral compression of the vertebral artery affects the contralateral cochlear blood flow more than the ipsilateral one.

並列關鍵字

vertebral artery ； cochlear blood flow ； microsphere