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鼻腔及鼻竇之腺樣囊狀癌

Adenoid Cystic Carcinoma of the Nasal Cavity and Paranasal Sinuses

摘要


原發於鼻腔及鼻竇的腺樣囊狀癌並不多見。它在早期即會有神經旁間隙(perineural space)侵犯,也常會有局部復發及40%以上的遠隔轉移率,加上此處複雜隱密的解剖位置,而使其成為頭頸部腺樣囊狀癌中預後最差的一群。 自1971年至1986年,本部共經歷了10例初發之鼻腔及鼻竇腺樣囊狀癌。追蹤至1991年10月止,共5例計9次之局部復發,4例有遠隔轉移,而有5例最後死於本疾病。局部控制率為33.3%,其中更有2例超過10年而無復發。治療上目前仍以積極廣泛之手術切除加上放射線治為較佳的治療方式。

關鍵字

腺樣囊狀癌 鼻竇

並列摘要


Primary adenoid cystic carcinoma of the nasal cavity and paranasal sinuses is rare. The tendency to spread along the perineural space, the high rate of local recurrence, and at least 40% distant metastatic rate, together with a complex anatomic situation, make its prognosis worse than that in any other area of the head and neck region. Between 1971 and 1986, 10 patients with adenoid cystic carcinoma of the nasal cavity and paranasal sinuses were primarily treated at VGH-Taipei. After long-term following-up, there were 9 local recurrences in 5 patients, 4 distant metastases, and 5 patients died of the disease. The local control rate was 33.3% and 2 patients were followed for more than 10 years without recurrence. Anatomically permitted wide surgical excision with adjuvant radiotherapy is the treatment of choice.

延伸閱讀


  • 張克昌、李振川、陳一豪、李國森、楊政謙、徐銘燦(1997)。鼻及鼻竇倒生性乳頭狀瘤之治療中華民國耳鼻喉科醫學會雜誌32(1),32-37。https://doi.org/10.6286/1997.32.1.32
  • Tai, S. Y., Chien, C. Y., Tai, C. F., Kuo, W. R., Huang, W. T., & Wang, L. F. (2007). 鼻中隔腺樣囊狀癌-病例報告. The Kaohsiung Journal of Medical Sciences, 23(8), 426-430. https://www.airitilibrary.com/Article/Detail?DocID=02575655-200708-23-8-426-430-a
  • 陳鴻鑫、李佳茹、黎瓊柱、蔡青劭(2009)。鼻-鼻竇之漿細胞瘤台灣耳鼻喉頭頸外科雜誌44(5),155-159。https://doi.org/10.6286/2009.44.5.155
  • 王聖琮、林厚鈞(2010)。Nasopharyngeal Carcinoma Presenting with Nasal Obstruction北市醫學雜誌7(2),167-172。https://doi.org/10.6200/TCMJ.2010.7.2.08
  • 王盛銘、劉步遠、王拯宗、江俊斌、郭英雄(1995)。Adenoid Cystic Carcinoma of the Salivary Gland中華民國口腔顎面外科學會雜誌6(1),A8-A28。https://doi.org/10.7104/CJOMS.199503.0010