- 期刊
頜下腺惡性混合瘤－病例報告
Malignant Mixed Tumor of the Submandibular Gland - Case Report
摘要
惡性混合瘤是一種少見的唾液腺惡性腫瘤，主要特徵就是病理切片上同時可見良性混合瘤和惡性細胞，且臨床上時常復發。由於惡性混和瘤可經由血液及淋巴轉移，半數患者有局部復發和遠處轉移現象，所以預後不佳。馬偕醫院於民國81年10月經歷1例頜下腺惡性混合瘤，在兩次手術切除後，因局部復發及吞嚥困難並合併肺、骨骼轉移，後給予頸部淋巴結廓清術才證實為惡性混合瘤，現於門診追蹤治療。今將其臨床表徵及病理作一文獻上回顧。
關鍵字
惡性混合瘤並列摘要
Malignant mixed tumor is a rare neoplasm of salivary gland. The patho-logical characteristic of this tumor is carci-noma within the benign pleomorphic adenoma. The prognosis of malignant mixed tumor is poor due to local recurrence and distant metastasis in half of these patients via hemtogenous and lymphogenous spread-ings. We reported a case of malignant mixed tumor of the submandibular gland with regional metastasis to the neck and distant metastasis to the lung and bone. The promary tumor and regional metastasis were treated surgically by wide excision and radical neck dissection. The literature concerning this rare neoplasm is reviewed and the clinical symptoms, treatment, pathological findings are also discussed.