- 期刊
鼻咽橫紋肌肉瘤併耳部侵犯－病例報告
Nasopharyngeal Rhabdomyosarcoma with Ear Involvement - Case Report
摘要
橫紋肌肉瘤是兒童最常見的軟組織肉瘤，約佔兒童所有惡性腫瘤的13%；常見於頭頸部、四肢、及泌尿道，而頭頸部是其最好發的部位，約有40%。過去頭頸部橫紋肌肉瘤的預後並不好，根治性手術非常困難，並常造成外觀及功能上的缺陷。在1972年，美國Intergroup Rhabdomyosarcoma Study提出多型式治療(multimodality therapy)的觀念，結合手術、化學治療及放射治療，使得橫紋肌肉瘤的存活率大大地提昇。高雄榮民總醫院於1994年3月經歷一橫紋肌肉瘤之病例，腫瘤從鼻咽部經耳咽管侵犯耳及外耳道。近10年來，國內外並無類似病例報告。病人接受鼻咽部腫瘤的部份切除後，接受化學治療及放射治療。今將其臨床表徵、放射診斷學、治療及預後，加以整理並提出討論。
關鍵字
橫紋肌肉瘤，鼻咽部，中耳並列摘要
Rhabdomyosarcoma is the most common soft tissue sarcoma in infants and children. The head and neck are the most common sites of involvement. Treatment for this neoplasm has undergone many changes. Up to date, a much improved prognosis has been got under the concept of combinations therapy with surgery, chemotherapy and radiation. In this article, we present a 19-year-old man with the tumor originating from the soft palate, nasopharynx, nasal cavity, extending to the middle ear cavity and external ear canal via the Eustachian tube. He received combination therapy including tumor debulking, 4 courses of multi-agent chemotherapy and radiotherapy. Fortunately, complete response resulted. The clinical features, treatment and prognosis of rhabdomyosarcoma were discussed.
延伸閱讀
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