喉癌或下咽癌病患的多發性原發瘤

Mutiple Primary Tumors in Patients with Laryngeal or Hypopharyngeal Cancers

黃瑞麟(Jui-Ling Huang) ； 呂紹榮(Shao-Jung Lu)

《中華民國耳鼻喉科醫學會雜誌》 30卷5期 (1995/10) Pp. 474-478

https://doi.org/10.6286/1995.30.5.474

摘要

近年來發生在上呼吸道與消化道的多發性原發瘤有愈來愈多的傾向，世界各地所報告的發生率為5至26%，原因可能與壽命之延長、腫瘤的早期發現及腫瘤治療技術的改進有關。本篇研究乃收集台北榮民總醫院從1970至1992年間喉癌與下咽癌共939例，其中包含多發性原發瘤患者47例。這些患者第一年存活率有72%，但5年存活率則降至21.3%，從發現第二原發瘤到死亡的平均存活時間為2.1年。發生第二原發瘤的位置與指標腫瘤(index tumor)有關，即喉癌患者多於肺部發現第二原發瘤，下咽癌患者則易在食道發現第二病灶。基於此，食道鏡與肺部X光追蹤檢查是十分重要的，對於提高多發性原發瘤的存活率必有很大的助益。

關鍵字

指標腫瘤，多發性原發瘤

並列摘要

The occurrence of multiple primary malignancies of the upper respiratory and digestive tract has become more and more in recent years, the incidence of various reports was 5-26%. It might be related to long life span, earlier diagnosis and improved therapeutic techniques.
This retrospective study was based on 939 cases of laryngeal and hypopharyngeal cancers and included 47 cases of multiple primary cancers treated between 1970 and 1992. These patients had a 72% chance of 1-year survival, but only 21.3% chance of 5-year survival. The average time from the diagnosis of second primary to the time of death was 2.1 years. The incidence of the second primary was related to the location of the index tumor, the lung was the most common site of second primary for laryngeal cancer and the esophagus for hypopharyngeal cancer, so esophagoscopy and chest radiological examination are very important for survival improving.

並列關鍵字

index tumor, multiple primary tumors