對於腦外傷病人於腦傷後體內內分泌改變的自然病程、流行病學及病理生理學只有少數的報告。本文報告一位無腎上腺自體免疫病、感染、出血及惡性腫瘤病史的嚴重腦外傷患者發生原發性腎上腺功能不全,呈現腦外傷引發原發性腎上腺功能不全的狀況。此特定病況或可稱之為「腦外傷併發原發性腎上腺功能不全」。
There have been isolated reports in the literature of the natural history and less than complete knowledge of the epidemiology and the pathophysiology of endocrine alteration occurring after traumatic brain injury (TBI). This article describes one primarily adrenal-dysfunction patient with severe TBI who had no evidence of present or prior adrenal autoimmune disease, infection, hemorrhage, or malignancy. It is suggested that this distinct condition can be labeled as ”primary adrenal insufficiency (PAI) developing after TBI”.