Clinical Experience in Treatment of Stevens-Johnson Syndorme

重症多形紅班亦稱史帝文生－強生症候群，其症狀的特點在於有多處黏膜病灶的發生，例如口腔，眼結膜及肛門生殖器之黏膜。這些症狀可以單獨發生但常合併廣泛的表皮壞死病徵，它常因為服用藥物或是感染而誘發症狀，並經常有高死亡率，由於史帝文生－強生症候群的症狀複雜且嚴重，治療這個疾病必須依病患個人的發病狀態做有經驗且具彈性的治療。從1991年至1997年之間，有七位史帝文生－強生症候群的病患在國泰醫院三個不同部門接受治療，只有四位病患在燒傷中心接受水療及早期覆蓋人工合成敷料，他們的治療結果和住院日數均較非燒傷中心治療病患之預後為佳。

關鍵字

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並列摘要

Erythema multiforme major, also known as Stevens-Johnson syndroms is characterized by severe involvement of more than one mucosal sites (oral, conjunctival, anogential), which may occur as an isolated finding but is more often accompanied by extensive necrotizing cutaneous lesions. It typically represents an episodic disease caused either by drug intolerance or prior infections, and often associated with a high mortality. Care of patient with Stevens-Johnson syndrome is difficult, complex, and requires a considerable degree of experience and flexibility to adjust for individual problems. Different treatment modalities were practiced by different specialist and no unifrom treatment is agreed by all. From 1991 to 1997, seven patients have been treated at Cathay General Hospital in three different departments with the same diagnosis. Only four patients underwent burn unit care. Whirpool hydrotherapy, and early extensive wound coverage with biosynthetic dressing (Biobrane) in plastic surgery division, which had short hospital stay and better result comparing to those treated at non-burn unit patients.

並列關鍵字

Stevens-Johnson syndrome ； erythema multiforme major ； necrotizing cutaneous lesion

國際替代計量

Clinical Experience in Treatment of Stevens-Johnson Syndorme

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