- 期刊
Aeromonas Sepsis in Severe Burn Patients
嚴重燒傷病患之産氣單胞菌敗血症
摘要
燒傷病患不常見産氣單胞菌感染，英語文獻中報告之案例不到二十位；自1993年1月至1999年4月，成功大學醫學院附設醫院燒傷中心有七位病患發生産氣單胞菌感染，其中兩位曾接觸過水制品，血液培養顯現産氣單胞菌菌血症，所有病患均出現敗血症之臨床表癥譬如發燒，低血壓，急性腎衰竭，意識狀態改變。雖然曾經接受痂皮切除手術及抗生術治療，但所有病患均死亡。本文亦討論此病原菌之微生物學，流行病學，致病生理學及治療方針。燒傷病患罕見産氣單胞菌感染，一旦發生將導致極高之死亡率，可達百分之百。因此若燒傷病患罹患此病菌感染並有敗血症應考慮更積極之手術處置，譬如筋膜切除手術，及第三代頭胞芽菌素合併胺基糖苷類抗生素治療。
關鍵字
無資料並列摘要
Aeromonas infection is uncommon in burn patients, with less than twenty cases reported in English literature. From January of 1993 to April of 1999, seven patients developed aeromonas infection at National Chen Kung University Hospital Burn Center. Among these patients, two had aquatic exposure. Blood cultures revealed aeromonas bacteremia. All of them demonstrated clinical manifestations of sepsis, such as fever, hypotension, acute renal failure, altered consciousness. None of them survived, in spite of the combination of medical therapy and surgical management with tangential excision and STSG. The microbiology, epidemiology, pathophysiology and therapy of this pathogen were also discussed. Aeromonas infection in burn patients is rare but may cause tremedous rate of mortality, up to 100%. According to the painful experience, we will try more aggressive surgical intervention, for example, fasciectomy on infectious burned lesions, and the third-generation cephalosporins combined with suitable aminoglycosides.
延伸閱讀
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