A Clinical Review of Esophageal Cancer: The First Report from Eastern Taiwan

食道癌之臨床回顧：臺灣東部首報

林憲宏(Hsien-Hong Lin) ； 柯龍吉(Long-Gee Ker) ； 黃呂津(Lu-Chin Huang) ； 黃士哲(Shih-Che Huang) ； 蔡伯文(Bo-Wen Tsai) ； 趙盛豐(Seng-Fong Chao) ； 李奕慧(Yi-Hwei Li)

《中華民國消化系醫學雜誌》 14卷4期 (1997/12) Pp. 318-325

https://doi.org/10.6557/GJTb.199712_14(4).0001

摘要

Esophageal cancer did not seem uncommon in eastern Taiwan, but there were no data available. In order to understand the clinical aspects of esophageal cancer in eastern Taiwan, we reviewed the charts of 82 consecutive cases of esophageal cancer admitted to this hospital in 7years. The average age was 62.8 years. There were 70 male and 12 female patients. The ethnic origin was Taiwanese in 46.0% of cases, aborigines in 36.5%, Mainland Chinese in 9.5%, and Hakka in 7.9%. The male to female ratio was 15/8 in aborigines, and 37/3 in non-aborigines (P＜0.01). Symptoms at diagnosis included: dysphagia, weight loss, chest pain, epigastric pain, neck mass, melena, hematemesis, cough, hemoptysis, and jaundice. Three cases had tongue cancer, buccal cancer, and laryngeal cancer prior to the index admission. The majority of cases (84.5%) were cigarette smokers, and 47.8% were alcoholic. Histologic diagnosis included squamous cell carcinoma (93.2%), adenocarcinoma (4.1%), small cell carcinoma (1.4%), and adenoid cystic carcinoma (1.4%). Five cases had esophagotracheal fistula. Distant metastasis was documented in 25 cases on admission. Surgery was performed in 50 cases, including 44 esophagectomies and 6 palliative operations. Postoperative complications were noted in 51.1% of cases. The 30-day operative mortality was 6.1%. The overall survival rate at.], 3, and 5 years was 38.4%, 14.3%, and 9.6% respectively (median survival: 6.9 months). Survival rate was significantly higher for cases with stage II disease and those receiving esophagectomy. In conclusion, the results of this review show that the prevalence of esophageal cancer among aborigines seems to be out of proportion to that among Taiwanese, Chinese, or Hakka, of which the reasons need further investigation.

關鍵字

食道癌 ； 東臺灣

並列摘要

Esophageal cancer did not seem uncommon in eastern Taiwan, but there were no data available. In order to understand the clinical aspects of esophageal cancer in eastern Taiwan, we reviewed the charts of 82 consecutive cases of esophageal cancer admitted to this hospital in 7years. The average age was 62.8 years. There were 70 male and 12 female patients. The ethnic origin was Taiwanese in 46.0% of cases, aborigines in 36.5%, Mainland Chinese in 9.5%, and Hakka in 7.9%. The male to female ratio was 15/8 in aborigines, and 37/3 in non-aborigines (P＜0.01). Symptoms at diagnosis included: dysphagia, weight loss, chest pain, epigastric pain, neck mass, melena, hematemesis, cough, hemoptysis, and jaundice. Three cases had tongue cancer, buccal cancer, and laryngeal cancer prior to the index admission. The majority of cases (84.5%) were cigarette smokers, and 47.8% were alcoholic. Histologic diagnosis included squamous cell carcinoma (93.2%), adenocarcinoma (4.1%), small cell carcinoma (1.4%), and adenoid cystic carcinoma (1.4%). Five cases had esophagotracheal fistula. Distant metastasis was documented in 25 cases on admission. Surgery was performed in 50 cases, including 44 esophagectomies and 6 palliative operations. Postoperative complications were noted in 51.1% of cases. The 30-day operative mortality was 6.1%. The overall survival rate at.], 3, and 5 years was 38.4%, 14.3%, and 9.6% respectively (median survival: 6.9 months). Survival rate was significantly higher for cases with stage II disease and those receiving esophagectomy. In conclusion, the results of this review show that the prevalence of esophageal cancer among aborigines seems to be out of proportion to that among Taiwanese, Chinese, or Hakka, of which the reasons need further investigation.

並列關鍵字

esophageal cancer ； eastern Taiwan