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摘要


Mirizzi氏症候群乃膽石症罕見但重要之併發症,因膽結石緊壓在膽囊頸或瞻囊管,造成總肝管受壓迫發炎,導致限塞性黃膽。回顧17位病人臨床病史、診斷過程、引流與手術處置,藉特徵性的膽管X光影像診斷Mirizzi氏症候群。自民國83年9月至民國88年8月,2095位病人接受ERCP檢查,其中17例(0.81%)經診斷為Mirizzi氏症候群第一型。病人平均年齡為58.1歲,女性病人有4位,15位病人接受手術。術前超音波Mirizzi氏症候群診斷率爲12%,電腦斷層Mirizzi氏症侯群診斷率爲14%。ERCP顯示5位之膽囊管與總肝管接合點偏低,9位手術病人有術前引流處置。兩位不適合手術者,一人接受長期總膽管支架放置,另一人在經皮穿肝膽道鏡手術後將膽囊管結石取出,有兩位病人在ERCP後有併發症。ERCP提供診斷、分類及手術參考,總膽管或膽囊之膽汁引流使病人得以在非緊急狀態下接受開刀治療,對於不適合手術者ERCP提供有效引流及結石取出之可能。膽石症病人發生Mirizzi氏症侯群的機率雖然不大,但若術前未做正確診斷,常造成術後總膽管狹窄等併發症。

並列摘要


Mirizzi's syndrome is a rare complication of cholelithiasis and consists of obstruction of the common hepatic duct due to a stone impacted in the cystic duct or gallbladder 2095 patients evaluated by endoscopic retrograde cholangiopancreatography (ERCP) in Tainan Municipal Hospital over the last 5 years yielded 17 cases (0.8%) suffering from Mirizzi's syndrome. 15 patients underwent surgical intervention. Their endoscopic retrograde cholangiograms, clinical features and outcome were reviewed. Seventeen patients had a cholangiographic diagnosis of Mirizzi's syndrome type I (McSherry's classification). Of these, 5 patients had a low cystic duct insertion with the common hepatic duct. The mean age was 58.1 years (range 36-98); 4 were females. 15 patients were referred for surgery and 9 of these patients had preliminary drainage. The detection rate of Mirizzi's syndrome was 12% in ultrasonography and 14% in computed tomography respectively. One patient received long term stenting, while extraction of the cystic duct stone was performed in the rest of the patients using a combination of percutaneous transhepatic cholangioscopic surgery and endoscopic therapy. Complications occurred in 2 of 17 cases after ERCE Preoperative diagnosis of Mirizzi's syndrome is important to plan a surgical strategy and to avoid complication. ERCP allows diagnosis and classifications of Mirizzi's syndrome; therapeutic endoscopy provides temporary biliary drainage and stones extraction in poor surgical risk candidates.

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