Changes of Gastric Mucosal Blood Flow in Gastric Ulcer Patients

胃潰瘍病人的胃粘膜血流之變化

莊哲男(Che-Nan Chuang) ； 王德宏(Teh-Hong Wang) ； 林肇堂(Jaw-Town Lin) ； 王正一(Cheng-Yi Wang) ； 陳定信(Ding-Shinn Chen) ； 宋瑞樓(Juei-Low Sung)

《中華民國消化系醫學會雜誌》 5卷2期 (1988/06) Pp. 64-69

https://doi.org/10.6557/GJTa.198806_5(2).0003

摘要

利用電解産生之氫氣及接觸型電極的方法，來測定30例正常人及29例胃潰瘍病人之胃粘膜血流。胃竇部的粗粘膜血流，在正常人與年齡成負相關(r=-0.66)，而在胃潰瘍之急性期時，比正常人有意義的減少，在治癒期有增高的傾向，在瘢痕期則高低不一。潰瘍邊緣之粗粘膜血流若與潰瘍週圍之正常粘膜來比較，在急性期時會降低，在治癒期時會增加，在瘢痕期時則降至正常或更低。我們認爲胃粘膜血流之減少在胃潰瘍之致病原因中扮演一個重要的角色，而胃粘膜血流之增加有助於潰瘍之癒合。

關鍵字

胃粘膜血流 ； 胃潰瘍 ； 氫氣廓清法

並列摘要

Gastric mucosal blood flow was measured in 30 normal persons and 29 patients with gastric ulcer using hydrogen gas generated by electrolysis and contact electrode method. Normal antral crude mucosal blood flow was negatively correlated with age. In patients with active gastric ulcer antral crude mucosal blood flow was significantly lower than in normal, and tended to be higher in healing stage and to be variable in scar stage. Crude mucosal blood flow in ulcer margin as compared with that of the periphery decreased in active stage, increased in healing stage and declined to normal or even lower values in scar stage suggesting that impaired mucosal blood flow played an important role in the pathogenesis of gastric ulcer and increased mucosal blood flow contributed to ulcer healing.

並列關鍵字

gastric mucosal blood flow ； gastric ulcer ； hydrogen gas clearance