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Hypertension after Transcatheter Hepatic Arterial Embolization in a Case of Carcinoid Syndrome

肝類癌症候羣病人施行肝動脈栓塞術後併發高血壓

摘要


此篇報告為一例有組織學及生化學檢查證實的肝類癌合併典型的類癌症候重,病人有水瀉,陣發性臉潮紅及血管擴張的症狀,生化檢查尿中5-羥基吲啋醋酸(5-hydroxyindole acetic acid)值及血清張力素(serotonin)值均昇高。一系列影像檢查發現肝兩葉有腫瘤,但未發現有其他原發性的類癌存在,肝腫瘤切片檢查則發現不完全及完全嗜銀性反應。為了控制類癌症候羣,病人接受肝經導管動脈栓塞術。術後症狀已有改善,卻發生陣發性高血壓現象;雖經藥物控制,但在栓塞後一個月,病人由於肝衰竭而死亡。

並列摘要


A case of histologically and biochemically proven hepatic carcinoid tumor with typical carcinoid syndrome was reported. The patient had symptoms and signs of diarrhea, telangiecrasis over cheeks and neck, and episodic flushing of face. He was found to have increased levels of5-hydroxyindole acetic acid in the urine and serotonin in serum. Serial examinations showed hepatic tumors in both lobes; however, other sources of the carcinoid tumor cannot be found. Histological studies of the tumor showed positive argyrophilic and argentaffinic reactions. He received transcatheter arterial embolization for control of the carcinoid syndrome. Transient hypertension was noted in the postembolization period and was controlled by medication. The patientfinally died of hepaticfailure one month after embolization with some improvement of the carcinoid syndrome had been achieved.

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