Zieve's syndrome has never been reported in Taiwan. It is a rare disease characterized by transient hyperlipemia, jaundice and hemolytic anemia in association with alcoholic liver disease. In this case, laboratory investigation revealed marked lipemia which normalized four days later. Hemoglobin dropped sharply from 15.5gm/dl to 7.3gmldl and was associated with hyperbilirubinemia of indirect type. The stool was negative for occult blood. The reticulocyte count increased. The red blood cell fragility test was within normal limits. Coomb's test was negative. Percutaneous liver biopsy showed fatty metamorphosis. The above statements are all similar to those described by Zieve in 1958.