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Cholangiographic CT in Differential Diagnosis of Caroli's Disease and Polycystic Liver Disease-A Preliminary Study

膽管電腦斷層攝影術於鑑別診斷卡羅裏氏症與多囊性肝病之運用

摘要


為了解膽管電腦斷層攝影術與肝膽核醫顯影術於鑑別診斷卡羅里氏症(Caroli's disease)與多囊性肝病(polycystic liver disease)之臨床價值,我們為1位卡羅里氏症患者與4位多囊性肝病患者進行上述二種檢查。這些進入研究之患者皆於事前經腹部超音波檢查與逆行性內視鏡膽管攝影術作了確定診斷。結果顯示:由顯影劑進入肝內囊狀病灶與否,膽管電腦斷層攝影術可以正確地診斷上述每一位患者。而肝膽核醫顯影術雖然可以正確診斷具卡羅里氏症的那位患者,但是在多囊性肝病之診上則不理想,有1位患者被誤以為是卡羅里氏症,有2位患者之影像未見任何不正常之發現。結論:膽管電腦斷層影術可以清楚地辨別卡羅里氏症與多囊性肝病,因此,在未來可作為鑑別診斷肝內多囊性病灶之非侵襲性檢查。

並列摘要


In order to investigate the clinical values of cholangiographic computed tomography (cholangiograhic CT) and hepatobiliary scintigraphy in the diagnosis of Caroli's disease and polycystic liver disease (PLD), we enrolled one patient with Caroli's disease and four patients with PLD confirmed by sonography and endoscopic retrograde cholangiography to undergo the above mentioned examinations. Based on the presence or absence of contrast opacification of intrahepatic cystic lesions, cholangiographic CT was able to make accurate diagnoses in all patients. On the other hand, hepatobiliary scintigraphy made an accurate diagnosis in the patient with Caroli's disease, but it failed to demonstrate abnormal findings in two patients with PLD and the image of another patient with PLD was misinterpreted as Caroli's disease. Our preliminary study suggested that cholangiographic CT was a promising non-invasive method to accurately differentiate Caroli's disease from PLD.

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