An analytical method integrating the parametric solid modeling and finite element analysis is employed to study the three dimensional vibrations of cantilevered twisted parallelepipeds with various configurations. The effects of different geometric parameters on the natural frequencies and vibration modes have been investigated and discussed. The results show that the length/depth and depth/thickness ratio affect significantly the order and possibility of vibration modes to appear, but the twisted angle merely influences the order. The natural frequency of each vibration mode is affected differently by the increasing twisted angle for twisted parallelepipeds with different length/depth and depth/thickness ratio.