Cervical Vertebrae Metastases in Oral Squamous Cell Carcinoma: A Case Report

口腔鱗狀上皮癌之頸椎轉移－病例報告

于恩浩(En-Hao Yu) ； 吳政憲(Cheng-Hsien Wu) ； 羅文良(Wen-Liang Lo) ； 高壽延(Shou-Yen Kao) ； 張哲壽(Che-Shoa Chang)

《臺灣口腔顎面外科學會雜誌》 19卷1期 (2008/03) Pp. 65-70

https://doi.org/10.7104/TJOMS.200803.0065

摘要

口腔鱗狀上皮癌發生頸椎轉移是很罕見的。現今由於治療方式的進步，在晚期口腔鱗狀上皮癌患者，雖然其局部復發情形有顯著的控制，但有愈來愈多的患者面臨了遠端轉移的情形。肺部、骨骼及肝等部位是口腔鱗狀上皮癌最常見的遠端轉移處。脊椎骨轉移相對來說很少見，最常發生在胸椎，接著是腰椎部位。本文報告一位晚期口腔鱗狀上皮癌之患者，在接受廣泛性切除手術、頸部淋巴清除手術及術後之放射、化學治療後，發生頸椎遠端轉移之情形，並針對頸椎轉移之診斷、可能機制、治療方式及預後等，進行文獻回顧。

關鍵字

口腔鱗狀上皮癌 ； 遠端轉移 ； 脊椎骨轉移

並列摘要

Cervical vertebrae metastases is rare in oral squamous cell carcinoma (OSCC). Due to the improvement of locoregional control in advanced OSCC by the advancement of treatment modality, more patients are faced with the risk of developing distant metastases. The lung, skeleton and liver are the most frequent sites of distant metastases in OSCC. Vertebrae metastases is relatively rare, and the most frequent site of vertebrae metastases is thoracic vertebrae, followed by lumbar vertebrae. In this article, a case of advanced OSCC who received local wide excision ± neck dissection and adjuvant concurrent chemo-radiotherapy with cervical vertebrae metastases is reported. A literature review on the diagnosis, possible mechanism, therapeutic modalities and prognosis is mentioned in this article.

並列關鍵字

oral squamous cell carcinoma ； distant metastases ； vertebrae metastases