A 52 y/o ma le patient was presented and was diagnosed of Oral Squamous Cell Carcinoma of the right molar buccal gingival area. Treatment consists of neck dissection with tumor excision and radiotherapy (4600 cGy). 6 months post operatively, the patient asked for oral functional reconstruction. Suggested treatment of choice is Vertical Distraction Osteogenesis but due to patient's financial consideration, we opted for Intra-osseo Vertical Distraction Device. Unfortunately, one month post-operative follow up using the Intra-osseo Vertical Distraction Device, presence of pathologic fracture of the right mandible was noted. Six months post-operatively, the patient underwent Fibular Osteoseptocutaneous Flap combined with simultaneous dental implants to reconstruct the defect area. After 3 years of follow up periods, the patient's condition is well and good with no ill signs and symptoms. In this case report, we further discuss the effects of post-radiotherapy to the mandible, the use of vertical distraction osteogenesis for reconstruction and its effect on the implant osseointegration.