結節性筋膜炎被誤診為梭狀細胞肉瘤－病例報告

Misdiagnosis of Nodular Fasciitis as Spindle Cell Sarcoma-A Case Report

柯惠馨(Hui-Hsin Ko) ； 王逸平(Yi-Ping Wang) ； 郭生興(Sang-Heng Kok) ； 李正喆(Jang-Jaer Lee)

《臺灣口腔顎面外科學會雜誌》 22卷2期 (2011/06) Pp. 83-92

https://doi.org/10.7104/TJOMS.201106.0083

摘要

結節性筋膜炎是一種良性，增生性的梭狀細胞疾病，通常位於皮下或肌肉筋膜上。臨床上，它大部份以有著良好邊界的軟組織腫塊來表現，並且會和周邊的組織有附著的現象。由於它具有快速生長的特性，顯微鏡下的表現爲豐富的細胞結構以及高度的有絲分裂活性。結節性筋膜炎在臨床或是病理上容易出現誤診爲梭狀細胞肉瘤，因此正確的診斷經常需要仰賴組織病理的觀察。本文提出一例發生在頰黏膜區域腫瘤，它院切片組織病理診斷爲肉瘤，但經本院病理切片覆核及手術完整切除後，最後確診爲結節性筋膜炎的病例，並進一步討論二者的鑑別診斷。

關鍵字

結節性筋膜炎 ； 梭狀細胞 ； 肉瘤

並列摘要

Nodular fasciitis is a benign, reactive, proliferative spindle-cell lesion, usually located at the subcutaneous tissues or muscle fascia. Clinically, it manifests as a soft-tissue mass with well-dened margins and xed to the adjacent structures. Because of its rapid growth rate, rich spindle cell cellularity and relatively high mitotic activity, nodular fasciitis is sometimes misdiagnosed as a spindle cell sarcoma. Accurate diagnosis is based only on histopathological examination. A rare case of nodular fasciitis of the buccal mucosa which was misdiagnosed as spindle cell sarcoma in a 58-year-old male patient is presented with further discussion of differential diagnosis of both tumors.

並列關鍵字

Nodular fasciitis ； Spindle cell ； Sarcoma