Hemangioendothelioma of the Oral Cavity Mimics Cystic Lesion- A Case Report

與囊腫病變相似之口內血管內皮瘤－病例報告

林裕珉(Yu-Min Lin) ； 柯政全(Edward Cheng-Chuan Ko) ； 陳玉昆(Yuk-Kwan Chen) ； 陳靜怡(Ching-Yi Chen) ； 陳中和(Chung-Ho Chen)

《臺灣口腔顎面外科學會雜誌》 27卷3期 (2016/09) Pp. 211-222

摘要

血管內皮瘤為一種血管來源具有潛在惡性表徵的腫瘤，其可能會表現出局部再發或者遠端轉移的現象。此腫瘤可能於不同部位出現，好發於軟組織、肝臟及肺臟。原發於口腔的血管內皮瘤是非常少見的，從文獻回顧發現，口內常好發位置為牙齦，且常伴隨鄰近齒槽骨不同程度的吸收。臨床上正確診斷出血管內皮瘤是具挑戰性的，因為其於臨床表徵具有多變性，亦即其可能與良性病灶如發炎性肉芽腫或惡性病灶如惡性肉瘤具有相似的臨床表徵。一般需要配合免疫組織學的分析才能確診血管內皮瘤。基於此腫瘤於生物學上的變化，治療選擇主要為含安全邊緣的手術切除。我們提出一例下顎血管內皮瘤於臨床與影像學上的特徵近似於根尖囊腫。

關鍵字

血管內皮瘤 ； 血管腫瘤

並列摘要

Hemangioendothelioma is a vascular neoplasm with potential malignant behavior, meaning that the tumor may exhibit local recurrence as well as distant metastasis. It may occur at various anatomic sites, most commonly in the soft tissue, and organs such as liver and lung. The occurrence in the oral cavity is rare, and from literature review, the tumor mostly presented in the gingiva and with occasional adjacent alveolar bone absorption to different extent. Correct diagnosis can be challenging clinically as it may have various clinical manifestation and mimics other pathology from benign entity as pyogenic granuloma to malignancy as sarcoma. Immunohistochemical staining for specific marker is usually needed for definite diagnosis. Surgical removal with safety margin is the first treatment choice. Here, we report a case of hemangioendothelioma in the lower jaw with clinical and radiographic features highly resembling radicular cyst.

並列關鍵字

Hemangioendothelioma ； Vascular neoplasm