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咀嚼組織間隙惡性單發性纖維瘤-病例報告

Malignant Solitary Fibrous Tumor in the Masticator Space-A Case Report

摘要


單發性纖維瘤是一種罕見的軟組織腫瘤,最早的文獻報告是發生在肋膜上,因此過去曾被認爲該腫瘤起源於肋膜或肋膜的軟組織,之後發現單發性纖維瘤也可發生在其他漿膜層上,在口腔及鄰近組織較爲少見。在本文的報告裡,病灶發生在咀嚼組織間隙中,且在影像中呈現完整莢膜包覆,和常見的多型性腺瘤相類似,診斷需有賴於特殊的免疫化學染色,且在鏡檢下須注意細胞型態是否有惡性的轉變;治療方面,仍是以手術切除爲主,本文報告即呈現此病例記載以及咀嚼組織間隙常見腫瘤做出整理介绍。

並列摘要


Solitary fibrous tumor is a rare soft tissue tumor. The earliest paper revealed it as a tumor originated from pleura. Even though it was considered a kind of tumor only originate from pleura and subpleura, but it was also found originating from other serosa in the past decades. It is even hardly to found in oral cavity and adjacent soft tissues. In our case, the lesion was found in the masticator space, and the image revealed it was capsulated which just like the accessory salivary gland tumor. The specific diagnosis counted on immunochemical stain. The observation under microscope is necessary to distinguish whether the histopathological appearance of tumor behavior malignantly. The surgical excision is still the golden guideline to manage the solitary fibrous tumor. Our report revealed this seldom malignant primary tumor of masticator space, and reviewed the literature to discuss the different lesion of masticator space and the management of the solitary fibrous tumor.

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