School health-promoting programs in Taiwan have been carried out for decades. This study aimed to examine the extents of and the related factors for engaging in health-promoting lifestyle and health behaviors among undergraduate students. A cross-sectional survey with purposive sampling was adopted. A self-reported questionnaire was administered to the students from six universities in central Taiwan. In total, 915 responded questionnaires were obtained. Among the six health behaviors, students scored highest on interpersonal support, followed by self-actualization, stress management, nutrition, exercise, and health responsibility. Whether enrolling in health care courses, the frequency of attending classes in the morning, the level of perceived health, and the level of psychological distress could significantly predict the extent of overall health-promoting lifestyle. In particular, whether enrolling in health care courses, the level of perceived health, and the level of psychological distress were also significant determinants of many health behaviors. The findings of this study would provide suggestions to improve undergraduates' overall health-promoting lifestyle and health behaviors.