牙科門診患者唾液念珠菌盛行率

The Prevalence of Salivary Candida in Dental Clinic Patients

陳育瑩(Yu-Ying Chen) ； 張天韻(Tien-Yun Chang) ； 莊傳宗(Chuan-Tsung Chuang) ； 王宜斌(Yi-Bing Wang)

《中華民國家庭牙醫學雜誌》 3卷1期 (2008/06) Pp. 37-44

https://doi.org/10.6566/JFD/2008.3(1).37

摘要

白色念珠菌(Candida albicans)感染是造成義齒口腔炎的主要原因。本實驗的目的在分析不同性別、年齡及佩帶活動義齒之牙科患者，其唾液內念珠菌數目是否有差異。本研究收集至三軍總醫院牙科就診之患者共159人，其中男性82人，女性77人。平均年齡47.1歲。受檢者將未刺激性唾液直接吐在無菌之收集瓶內。唾液樣本用磷酸緩衝液稀釋後，接種在Sabouraud's agar plate上，置於空氣中在37℃下培養兩天。然後記錄培養基上之菌落數目。結果顯示：白色念珠菌帶菌率在四組不同年齡層分別為：0到19歲為40%，20至39歲為70.9%，40到59歲為77.8%，大於60歲族群為91.9%。唾液中白色念珠菌數目男性比女性高，年齡越大的人念珠菌數目也越多。40歲以上女性佩戴義齒者，念珠菌數目比未佩戴義齒者多。而男性大於60歲之患者，不論有無佩戴活動義齒，其念珠菌數目皆無差別。由本實驗結果推論：唾液中念珠菌數目除了與性別、年齡及配戴活動義齒有關外，亦可能與唾液分泌量與口腔衛生等其他因素有關聯。

關鍵字

義齒性口腔炎 ； 白色念珠菌 ； 未刺激性唾液 ； 帶菌者

並列摘要

Denture stomatitis is common in denture wearers. Candida albicans is well-established as a contributory factor in the etiology of denture stomatitis. The aim of this study was to examine the effect of age, sex and denture-wearing on the oral candidal population in unstimulated whole saliva. A total of 159 (82 males, 77 females, average 47.1 years old) participants who visited Dental Department of Tri-service General Hospital were examined. The subjects were divided into four age groups: 0-19 years, 20-39 years, 40-59 years, and ＞ 60 years. Samples of unstimulated whole saliva were cultured on Sabouraud's agar plate and incubated at 37℃ in air for 2 days. The colony forming units (CFU) on culture plate were enumerated.
Results show that male had higher CFU of Candida in saliva compared to female. The isolation frequency and viable counts of yeast in saliva were consistently increased with age. In those aged of over 40 years, female denture-wearer had higher CFU of candida in saliva compared to non-denture wear individuals. In male age of over 60 years, there is no difference between denture-wearers and non-denture-wearers. Collectively, the data show that the salivary yeasts in health persons can be independently influenced by age, sex and the wearing of dentures.

並列關鍵字

denture stomatitis ； Candida albicans ； unstimulated whole saliva ； carriers