運動對血漿飢餓素濃度影響之探討

A Probe of Effect of Plasma Ghrelin Level on Exercise

陳建瑋(Chien-Wei Chen) ； 劉立宇(Li-Yu Liu)

《臺南大學體育學報》 5期 (2010/12) Pp. 18-31

https://doi.org/10.29740/JPENUT.201012.0002

摘要

飢餓素(ghrelin)是一種由28個胺基酸所組成的多胜肽激素，由胃的基底層所分泌，由於會增加食慾與促進食物攝取，所以在減重上扮演著重要角色。目前的研究顯示單次運動所造成飢餓激素濃度的改變還沒有一致的結果，或許是因爲受試者的不同或參雜了其他生理反應所引起的，有待後續更多研究以釐清飢餓素之效應。但對於長期運動參與者而言，運動後體重減輕會伴隨體內飢餓素濃度有上升的現象出現，但這上升的現象只是要補償體內負能量平衡的狀況，所以當體內能量平衡後，體內飢餓素濃度便會自發性的下降，從而降低食慾，以達到持續維持減重後體重之目的；而另一種減重方式，節食也會造成體重下降，但若以節食但不運動的方式來減重，雖能達減重之目的，但體內飢餓素濃度在減重後會有上升的情形出現，且上升的幅度還會高於減重前的水準，這將會大量促進食慾，導致有復胖的風險發生。從長期運動或節食造成飢餓素濃度在體內變化的情形可說明飢餓素在減重上的確扮演著重要的角色，僅靠節食想達到減重的目的並不是最好的辦法，必須配合運動才能在長時間減重上達到良好的效果。

關鍵字

減重 ； 節食 ； 復胖

並列摘要

Ghrelin, a 28 amino acid peptide secreted by the gastric fundus. Ghrelin potently stimulates appetite and promote food intake, so ghrelin acts as a key role in regulating weight loss. In contrast, previous research has given contradictory results, showing ghrelin levels after an acute exercise. The reasons for the contradictory results are complex and incompletely physiological responses or difference between subjects. Further studies are needed to fully elucidate this contradiction. For long-term exercise participants, weight loss by long-term exercise is associated with an increase in ghrelin level, this phenomenon is compensate for the negative energy balance in the body. When energy balance is stabilized at a new, ghrelin concentrations return to basal levels, and then reduced appetite, that can be achieved weight maintenance by active weight reduction. Another weight loss method was food restriction. Although this method is effective in weight loss, but usually accompanies increased ghrelin level. This phenomenon will lead to potently increased appetite, that a factor was contributed to weight regain risk. In summary, ghrelin levels change with long-term exercise or food restriction can explain role for ghrelin in the adaptive response weight loss. Dependent food restriction to achieve the weight loss is not the best way, must be combined with exercise can achieve the effective weight loss.

並列關鍵字

weight loss ； food restriction ； weight regain