Mucosa-related Lymphoid Tissue Lymphoma of the Parotid Gland-Case Report and Literature Review

腮腺長出的黏膜相關淋巴組織淋巴瘤—個案報告及文獻回顧

王樹偉(Shu-Wei Wang) ； 李俊達(Jiunn-Tat Lee) ； 鄭立福(Li-Fu Cheng) ； 王健興(Chien-Hsing Wang) ； 孫宗伯(Tzong-Bor Sun) ； 吳孟熹(Meng-Si Wu) ； 曾國藩(Guo-Fang Tseng) ； 簡守信(Sou-Hsin Chien)

《臺灣整形外科醫學會雜誌》 21卷1期 (2012/03) Pp. 54-59

https://doi.org/10.7096/TJTSPS.201203.0054

摘要

背景：黏膜相關淋巴組織淋巴瘤（Mucosa-related lymphoid tissue lymphoma）是少見的低惡度性B細胞淋巴瘤，通常是從腸胃道長出來。這類淋巴瘤從腮腺長出是很少見的情形。目的及目標：提出從腮腺長出之黏膜相關淋巴組織淋巴瘤疾病及討論其治療及預後。材料及方法：我們提出一位77歲的男性病患，他長達十個月於右耳前方有一慢性擴大的不痛的腫瘤。腫瘤大小為4cm x 3 cm，位於右側腮腺，並有另一顆直徑1.7cm的腫瘤位於腮腺下半部。腫瘤切除部份我們施行了表淺性腮腺切除術，並於術後佐以放射線治療。持續追蹤病患並無復發。結果：在11個月的術後追蹤期間，我們並未發現局部復發及遠端轉移。結論：黏膜相關淋巴組織淋巴瘤很長從腮腺長出。術前的疾病診斷是很困難的，在病人有危險因子時，必須要懷疑這類疾病之可能性。保守性的表淺性腮腺切除術，可以同時達到診斷及治療的目的。疾病如果限制在局部病灶並沒有擴散，建議可以實施放射線治療，而在比較擴散的疾病，建議實施化學治療。在治療之後予以積極的追蹤，其預後通常是很好的。

並列摘要

Background:Mucosa-related lymphoid tissue (MALT) lymphomas are rare low-grade B-cell lymphomas, mostly arising from the gastrointestinal tract. MALT lymphomas arising from the parotid gland are very rare.Aim and objective:We report the rare condition of mucosa-related lymphoid tissue lymphoma arising from the parotid gland and discuss their treatment and outcome.Material and Methods:A 77-year-old man presents with a 10-month history of a slow growing painless tumor at his right periauricular area. It measured 4 x 3 cm in size. There were another two palpable tumors at lower pole of the parotid gland, with the largest one measuring 1.7cm. After excisional biopsy of the minor tumors at the lower pole. The pathology confirmed MALT lymphoma. Superficial parotidectomy with concurrent radiation therapy was done.Results:There was no evidence of local recurrence and distant metastasis on the 11 months follow-up.Conclusion:Mucosa-associated lymphoid tissue lymphoma is rarely arising from the parotid gland. Diagnosis of the disease is very difficult and should be suspected if a patient has significant risk factors. Conservative superficial parotidectomy is recommended both for diagnosis and treatment. Radiation therapy is recommended for limited stages of the disease with systemic chemotherapy advised for advanced stage. Prognosis is favorable with careful post-treatment follow-up.

並列關鍵字

mucosa-related lymphoid tissue lymphoma ； parotid gland