|
參考文獻
Assaraf, Y.G., Schimke, R.T. (1987). Identification of methotrexate transport deficiency in mammalian cells using fluoresceinated methotrexate and flow cytometry. Proc Natl Acad Sci U S A Oct;84(20):7154-8.
Backliwal, G., Hildinger, M., Chenuet, S., Wulhfard, S., De Jesus, M., Wurm, F. M. (2008). Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1g/l by transient transfection under serum-free conditions. Nucleic Acids Res 36(15):e96.
Bebbington, C.R., Renner, G., Thomson, S., King, D., Abrams, D., Yarranton, G.T. (1992). High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker. Biotechnology (N Y) Feb;10(2):169-75.
Bell, A.C., Felsenfeld, G. (1999). Stopped at the border: boundaries and insulators. Curr Opin Genet Dev. Apr;9(2):191-8.
Benton, T., Chen, T., McEntee, M., Fox, B., King, D., Crombie, R., Thomas, T.C., Bebbington, C. (2002). The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein. Cytotechnology Jan;38(1-3):43-6.
Bright, R.A., Ross, T.M., Subbarao, K., Robinson, H.L., Katz, J.M. (2003). Impact of glycosylation on the immunogenicity of a DNA-based influenza H5 HA vaccine. Virology Apr 10;308(2):270-8.
Brummelkamp, T.R., Bernards, R., Agami, R. (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science Apr 19;296(5567):550-3. Epub Mar 21.
Butler, M. (2005). Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals. Appl Microbiol Biotechnol Aug;68(3):283-91. Epub Apr 16.
Cacciatore, J.J., Chasin, L.A., Leonard, E.F. (2010). Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system. Biotechnol Adv. Apr 21.
Chambers, T.M., Kawaoka, Y., Webster, R.G. (1988). Protection of chickens from lethal influenza infection by vaccinia-experssed hemagglutinin. Virology 167(2):414-421.
Chang, C.Y., Hong, W.W., Chong, P., Wu, S.C. (2006). Influence of intron and exon splicing enhancers on mammalian cell expression of a truncated spike protein of SARS-CoV and its implication for subunit vaccine development. Vaccine Feb 20;24(8):1132-41. Epub 2005 Sep 16.
Chen, C., Chasin, L.A. (1998). Cointegration of DNA molecules introduced into mammalian cells by electroporation. Somat Cell Mol Genet Sep;24(5):313.
Chung, J.Y., Kim, T.K., Lee, G.M. (2000). Morphological selection of parental Chinese hamster ovary cell clones exhibiting high-level expression of recombinant protein. Korea Advanced Institute of Science and Technology, Taejon, Korea.
Cockett, M.I., Bebbington, C.R., Yarranton, G.T. (1990). High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. Biotechnology (N Y) Jul;8(7):662-7.
Crawford, J., Wilkinson, B., Vosnesensky, A., Smith, G., Garcia, M., Stone, H., Perdue, M.L. (1999). Baculovirus-derived hemmagglutinin vaccines protect against lethal influenza infections by H5 and H7 subtypes. Vaccine 17(18):2265-2274.
Cullen, B. R. (2006). Induction of stable RNA interference in mammalian cells. Gene therapy 13, 503-508.
De, B.K., Shaw, M.W., Rota, P.A., Harmon, M.W., Esposito, J.J., Rott, R., Cox, N.J., Kendal, A.P. (1988). Protection against virulent H5 avian influenza virus infection in chickens by an inactivated vaccine produced with recombinant vaccinia virus. Vaccine 6(3):257-261.
Dykxhoorn, D.M., Novina, C.D., Sharp, P.A. (2003). Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol Jun;4(6):457-67.
Fire, A., Xu, S., Montgomery, M.K., Kostas, S.A., Driver, S.E., Mello, C.C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature Feb 19;391(6669):806-11.
Gandor, C., Leist, C., Fiechter, A., Asselbergs, F.A. (1995). Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells. FEBS Lett Dec 27;377(3):290-4.
Genzel, Y., Reichl, U. (2009). Continuous cell lines as a production system for influenza vaccines. Expert Rev Vaccines. Dec;8(12):1681-92.
Girod, P.A., Nguyen, D.Q., Calabrese, D., Puttini, S., Grandjean, M., Martinet, D., Regamey, A., Saugy, D., Beckmann, J.S., Bucher, P., Mermod, N. (2007). Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells. Nat Methods Sep;4(9):747-53. Epub Aug 5.
Gwizdek, C., Ossareh-Nazari, B., Brownawell, A.M., Doglio, A., Bertrand, E., Macara, I.G., Dargemont, C. (2003). Exportin-5 mediates nuclear export of minihelix-containing RNAs. J Biol Chem Feb 21;278(8):5505-8. Epub Dec 30.
Haber, D.A., Beverley, S.M., Kiely, M.L., Schimke, R.T. (1981). Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts. J Biol Chem Sep 25;256(18):9501-10.
Hartshorn, K.L., Webby, R., White, M.R., Tecle, T., Pan, C., Boucher, S., Moreland, R.J., Crouch, E.C., Scheule, R.K. (2008). Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D. Respir Res Sep 23;9:65.
Henikoff, S. (1992). Position effect and related phenomena. Curr Opin Genet Dev. 1992 Dec;2(6):907-12.
Hong, W.W., Wu, S.C. (2007). A novel RNA silencing vector to improve antigen expression and stability in Chinese hamster ovary cells. Vaccine May 16;25(20):4103-11. Epub Feb 26.
Hong, W.W., Yen, Y.H., Wu, S.C. (2007). Enhanced antibody affinity to Japanese encephalitis virus E protein by phage display. Biochem Biophys Res Commun Apr 27;356(1):124-8. Epub Mar 1.
Horimoto, T., Kawaoka, Y. (2005). Influenza: lessons from past pandemics, warnings from current incidents. Nat Rev Microbiol Aug;3(8):591-600.
Huang, Y., Li, Y., Wang, Y.G., Gu, X., Wang, Y., Shen, B.F. (2007). An efficient and targeted gene integration system for high-level antibody expression. J Immunol Methods Apr 30;322(1-2):28-39. Epub Feb 26.
Ito, T., Kawaoka, Y. (2000). Host-range barrier of influenza A viruses. Vet Microbiol May 22;74(1-2):71-5.
Jayapal, K.P., Wlaschin, K.F., Hu, W.S., Yap, M.G.S. (2007). Recombinant protein therapeutics from CHO cells-20 years and counting. Chem Eng Prog 103:40-52.
Jun, S.C., Kim, M.S., Hong, H.J., Lee, G.M. (2006). Limitations to the development of humanized antibody producing Chinese hamster ovary cells using glutamine synthetase-mediated gene amplification. Biotechnol Prog May-Jun;22(3):770-80.
Kalthoff, D., Giritch, A., Geisler, K., Bettmann, U., Klimyuk, V., Hehnen, H.R., Gleba, Y., Beer, M. (2010). Immunization with plant-expressed hemagglutinin protects chickens from lethal highly pathogenic avian influenza virus H5N1 challenge infection. J Virol. Nov;84(22):12002-10. Epub 2010 Sep 1.
Kaufman, R.J. (1990). Selection and coamplification of heterologous genes in mammalian cells. Methods Enzymol 185:537-66.
Kaufman, R.J., Schimke, R.T. (1981). Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line. Mol cell boil 1(12):1069-76.
Kellems, R.E. (1991). Gene amplification in mammalian cells: strategies for protein production. Curr Opin Biotechnol Oct;2(5):723-9.
Khurana, S., Verma, S., Verma, N., Crevar, C.J., Carter, D.M., Manischewitz, J., King, L.R., Ross, T.M., Golding, H. (2010). Properly folded bacterially expressed H1N1 hemagglutinin globular head and ectodomain vaccines protect ferrets against H1N1 pandemic influenza virus. PLoS One. Jul 12;5(7):e11548.
Kim, J.M., Kim, J.S., Park, D.H., Kang, H.S., Yoon, J., Baek, K., Yoon, Y. (2004). Improved recombinant gene expression in CHO cells using matrix attachment regions. J Biotechnol Jan 22;107(2):95-105.
Kito, M., Itami, S., Fukano, Y., Yamana, K., Shibui, T. (2002). Construction of engineered CHO strains for high-level production of recombinant proteins. Appl Microbiol Biotechnol. Dec;60(4):442-8.
Kwaks, T.H., Barnett, P., Hemrika, W., Siersma, T., Sewalt, R.G., Satijn, D.P., Brons, J.F., van Blokland, R., Kwakman, P., Kruckeberg, A.L., Kelder, A., Otte, A.P. (2003). Identification of anti-repressor elements that confer high and stable protein production in mammalian cells. Nat Biotechnol May;21(5):553-8. Epub Apr 7.
Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Rådmark, O., Kim, S., Kim, V.N. (2003). The nuclear RNase III Drosha initiates microRNA processing. Nature Sep 25;425(6956):415-9.
Lim, S.F., Chuan, K.H., Liu, S., Loh, S.O., Chung, B.Y., Ong, C.C., Song, Z. (2006). RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cells. Metab Eng Nov;8(6):509-22. Epub Jun 7.
Lin, S. C., Leng, C.H., Wu, S.C. (2010). Generating stable Chinese hamster ovary cell clones to produce a truncated SARS-CoV spike protein for vaccine development. Biotechnol Prog. Nov-Dec;26(6):1733-40. doi: 10.1002/btpr.480.
Lin, Y.J., Deng, M.C., Wu, S.H., Chen, Y.L., Cheng, H.C., Chang, C.Y., Lee, M.S., Chien, M.S., Huang, C.C. (2008). Baculovirus-derived hemagglutinin vaccine protects chickens from lethal homologous virus H5N1 challenge. J Vet Med Sci. Nov;70(11):1147-52.
Loureiro, S., Ren, J., Phapugrangkul, P., Colaco, C.A., Bailey, C.R., Shelton, H., Molesti, E., Temperton, N.J., Barclay, W.S., Jones, I.M. (2010). Adjuvant free immunisation with Hemagglutinin-Fc fusion proteins as an approach to influenza vaccines. J Virol. Dec 29.
McManus, M.T., Sharp, P.A. (2002). Gene silencing in mammals by small interfering RNAs. Nat Rev Genet Oct;3(10):737-47.
Moremen, K. W. & Molinari, M. (2006). N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control. Curr opin struct Biol 16, 592-599.
Mori, K., Kuni-Kamochi, R., Yamane-Ohnuki, N., Wakitani, M., Yamano, K., Imai, H., Kanda, Y., Niwa, R., Iida, S., Uchida, K., Shitara, K., Satoh, M. (2004). Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA. Biotechnol Bioeng Dec 30;88(7):901-8.
Morrow, J.K. (2008). Optimizing transient gene expression: applications expected to move beyond discovery and the preclinical to clinical realm. Gene Eng Biotechnol News 28(5):54-9.
Ng, S.K., Lin, W., Sachdeva, R., Wang, D.I., Yap, M.G. (2010). Vector fragmentation: characterizing vector integrity in transfected clones by Southern blotting. Biotechnol Prog Jan;26(1):11-20.
Ng, S.K., Wang, D.I., Yap, M.G. (2007). Application of destabilizing sequences on selection marker for improved recombinant protein productivity in CHO-DG44. Metab Eng May;9(3):304-16. Epub Feb 14.
Novina,C.D., Sharp, P.A. (2004). The RNAi revolution. Nature Jul 8;430(6996):161-4.
Omasa, T. (2002). Gene amplification and its application in cell and tissue engineering. J Biosci Bioeng 94(6):600-5.
Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J., Conklin, D.S. (2002). Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev Apr 15;16(8):948-58.
Page, M.J., Sydenham, M.A. (1991). High level expression of the humanized monoclonal antibody Campath-1H in Chinese hamster ovary cells. Biotechnology (N Y) Jan;9(1):64-8.
Pallavicini, M.G., Rosette, C., Reitsma, M., Deteresa, P.S., Gray, J.W. (1990). Relationship of c-myc gene copy number and gene expression: cellular effects of elevated c-myc protein. J Cell Physiol May;143(2):372-80.
Pearson, S. (2007). Producing protein therapeutics by mammalian cell culture. Bioprocess Int 5:30-7.
Running Deer, J., Allison, D.S. (2004). High-level expression of proteins in mammalian cells using transcription regulatory sequences from the Chinese hamster EF-1alpha gene. Biotechnol Prog May-Jun;20(3):880-9.
Schimke, R.T., Alt, F.W., Kellems, R.E., Kaufman, R.J., Bertino, J.R. (1978). Amplification of dihydrofolate reductase genes in methotrexate-resistant cultured mouse cells. Cold Spring Harb Symp Quant Biol 42 Pt 2:649-57.
Schuck, S., Manninen, A., Honsho, M., Füllekrug, J., Simons, K. (2004). Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference. Proc Natl Acad Sci U S A Apr 6;101(14):4912-7. Epub Mar 29.
Schultz-Cherry, S., Dybing, J.K., Davis, N.L., Williamson, C., Suarez, D.L., Johnston, R., Perdue, M.L. (2000). Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses. Virology 278(1):55-59.
Seth, G., Charaniya, S., Wlaschin, K.F., Hu, W.S. (2007). In pursuit of a super producer-alternative paths to high producing recombinant mammalian cells. Curr Opin Biotechnol Dec;18(6):557-64. Epub Dec 21.
Shoji, Y., Farrance, C.E., Bi, H., Shamloul, M., Green, B., Manceva, S., Rhee, A., Ugulava, N., Roy, G., Musiychuk, K., Chichester, J.A., Mett, V., Yusibov, V. (2009). Immunogenicity of hemagglutinin from A/Bar-headed Goose/Qinghai/1A/05 and A/Anhui/1/05 strains of H5N1 influenza viruses produced in Nicotiana benthamiana plants. Vaccine. May 26;27(25-26):3467-70. Epub 2009 Feb 5.
Skehel, J.J., Stevens, D.J., Daniels, R.S., Douglas, A.R., Knossow, M., Wilson, I.A., Wiley, D.C. (1984). A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody. Proc Natl Acad Sci U S A Mar;81(6):1779-83.
Skehel, J.J., Wiley, D.C. (2000). Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu Rev Biochem ;69:531-69.
Song, L., Zhang, Y., Yun, N.E., Poussard, A.L., Smith, J.N., Smith, J.K., Borisevich, V., Linde, J.J., Zacks, M.A., Li, H., Kavita, U., Reiserova, L., Liu, X., Dumuren, K., Balasubramanian, B., Weaver, B., Parent. J., Umlauf, S., Liu, G., Huleatt, J., Tussey, L., Paessler, S. (2009). Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin. Vaccine. Sep 25;27(42):5875-84. Epub 2009 Aug 3.
Sung, Y.H., Hwang, S.J., Lee, G.M. (2005). Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. Metab Eng Sep-Nov;7(5-6):457-66. Epub Sep 19.
Swayne, D.E., Kapczynski, D. (2008). Strategies and challenges for eliciting immunity against avian influenza virus in birds. Immunol Rev Oct;225:314-31.
Urlaub, G., Chasin, L.A. (1980). Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc Natl Acad Sci U S A. Jul;77(7):4216-20.
Walsh, G., Jefferis, R. (2006). Post-translational modifications in the context of therapeutic proteins. Nature biotechnology 24, 1241-1252.
Walsh, G. (2006). Biopharmaceuticals: recent approvals and likely directions. Trends Biotechnol 23, 553-8.
Wang, C.C., Chen, J.R., Tseng, Y.C., Hsu, C.H., Hung, Y.F., Chen, S.W., Chen, C.M., Khoo, K.H., Cheng, T.J., Cheng, Y.S., Jan, J.T., Wu, C.Y., Ma, C., Wong, C.H. (2009). Glycans on influenza hemagglutinin affect receptor binding and immune response. Proc Natl Acad Sci U S A. Oct 27;106(43):18137-42. Epub 2009 Oct 12.
Wei, C.J., Xu, L., Kong, W.P., Shi, W., Canis, K., Stevens, J., Yang, Z.Y., Dell, A., Haslam, S.M., Wilson, I.A., Nabel, G.J. (2008). Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. J Virol. Jul;82(13):6200-8. Epub 2008 Apr 16.
White, J., Kartenbeck, J., Helenius, A. (1982). Membrane fusion activity of influenza virus. EMBO J ;1(2):217-22.
Wu, S.C. (2009). RNA interference technology to improve recombinant protein production in Chinese hamster ovary cells. Biotechnol Adv. Jul-Aug;27(4):417-22. Epub 2009 Mar 14.
Wu, S.C., Hong, W.W., Liu, J.H. (2008). Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells. Vaccine Sep 8;26(38):4969-74. Epub Jul 9.
Wurm, F.M. (2004). Production of recombinant protein therapeutics in cultivated mammalian cells. Nat Biotechnol 22, 1393-1398.
Wurm, F.M., Gwinn, K.A., Kingston, R.E. (1986). Inducible overproduction of the mouse c-myc protein in mammalian cells. Proc Natl Acad Sci U S A Aug;83(15):5414-8.
Yi, R., Qin, Y., Macara, I.G., Cullen, B.R. (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev Dec 15;17(24):3011-6. Epub Dec 17.
Yoshikawa, T., Nakanishi, F., Ogura, Y., Oi, D., Omasa, T., Katakura, Y., Kishimoto, M., Suga, K. (2000). Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes. Biotechnol prog Sep-Oct；16(5):710-5.
Zahn-Zabal, M., Kobr, M., Girod, P.A., Imhof, M., Chatellard, P., de Jesus, M., Wurm, F., Mermod, N. (2001). Development of stable cell lines for production or regulated expression using matrix attachment regions. J Biotechnol Apr 27;87(1):29-42.
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