- 期刊
- OpenAccess
Codon Usage in Amoeba proteus Significantly Differs from Entamoeba histolytica and Acanthamoeba castellanii
並列摘要
Codon usage analysis performed on 5718 expressing codons (including stop codons) of nine Amoeba proteus proteins deposited in GenBank revealed that there was no bias in A. proteus codon usage and nucleotide frequencies in the three codon positions. This contrasts with codon usage in other amoebozoans, such as Acanthamoeba castellanii and Entamoeba histolytica, which are biased towards GC and AT, respectively. Interestingly, codon usage in A. proteus resembled that of human and Escherichia coli. The presence of tRNAs for all possible codons indicates that all heterologous genes may be expressed in these giant cells. However, based on this analysis it is impossible to deduce whether the observed differences and/or similarities are due to conservation or convergence.
延伸閱讀
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