- 期刊
Rapid Recovery of Spontaneous Baroreflex after Sevoflurane Anesthesia in Ambulatory Surgery
使用麻醉氣體Sevoflurane對門診手術病人自主神經恢複的影響
摘要
背景：Sevoflurane具備作用快，甦醒快，代謝快且不影響心血管及呼吸系統等待性。本實驗目的在評估sevoflurane用於門診手術麻醉後自主感壓反射恢複的情形。 方法：記錄10位麻醉體位評議爲壹級且接受常規門診婦科子宮內膜刮除術的病人之動脈壓訊號和心跳R-R interval，利用序列分析(sequence analysis)計算自主感壓反射敏感度(spontaneous baroreflex sensitivity, SBR)，比較術前、術中、術後5分鍾及術後10分鍾所得到之SBR值之差異。 結果：術中(12.2±2.1 ms/mmHg)及術後5分鈡(15.8±1.8 ms/mmHg)和術前(28.6±4.9ms/mmHg)有明顯差異。術後10分鍾(28.8±5.7 ms/mmHg)和術前則無明顯差異。 結論：使用麻醉氣體sevoflurane對門診手術病人之自主神經系統的影響，於關麻藥後10分鍾內即恢複術前清醒時之感壓反射強度。
並列摘要
Background: Although sevoflurane seems to have fulfilled the criteria of ideal anesthetic agent for ambulatory surgery, its effects on intraoperative alteration and postoperative recovery of arterial b aroreflex have not been well documented. This study assessed the time required for patients anesthetized with sevoflurane to regain their baseline baroreflex after ambulatory surge ties. Methods: Ten ASA class I female patients scheduled for minor gynecological operation (D&C) were enrolled in this study. Spontaneous baroreflex sensitivity (SBR) calculated by sequence analysis of beat-to-beat variations in systolic arterial pressure and R-R intervals was recorded before anesthesia (Baseline), during anesthesia (Anesthesia), five mm after operation (Post-op 1) and ten min after operation (Post-op 2). Data obtained from Anesthesia, Post-op 1, and Post-op 2 was compared with the Baseline. Results: SBR value determined in Baseline group (28.6±4.9 ms/mmHg) was significantly different from Anesthesia group (12.2±2.1 ms/mniHg) and Post-op 1 group (15.8±1.8 ms/mmHg). Patients regained their conscious baseline baroreflex sensitivity within ten miii after sevoflurane was switched off. Conclusions: Sevoflurane anesthesia depresses SBR and provides a quick SBR recovery upon emergence.
延伸閱讀
- Chang, Y., Lin, S. Y., Susetio, L., Hu, J. W., Hsu, H. W., & Liu, C. C. (1994). 吸入性全身麻醉時以Propofol應用於麻醉恢復. Acta Anaesthesiologica Sinica, 32(2), 89-94. https://www.airitilibrary.com/Article/Detail?DocID=P20170519003-199406-201904190012-201904190012-89-94
- 林嘉祥、林億守、劉正鴻、王祈斐、吳弘山、劉朝貴、陳龍華（1995）。手術中使用Propofol合併笑氣麻醉對體温調節閾值之研究。Acta Anaesthesiologica Sinica，33(1)，15-20。https://www.airitilibrary.com/Article/Detail?DocID=P20170519003-199503-201904180014-201904180014-15-20
- Li, S. H., Li, S. N., Shih, H. Y., Chiou, S. F., & Yi, H. D. (2004). 局部抽氣裝置對手術房麻醉廢氣移除之效能評估. Acta Anaesthesiologica Taiwanica, 42(2), 61-67. https://www.airitilibrary.com/Article/Detail?DocID=02541319-200406-42-2-61-67-a
- Chen, T. L., Yang, S. F., Chang, H. C., Tai, Y. T., Li, N. L., & Lin, C. J. (1998). 使用Sevoflurane及Isoflurane於中國人成年病患麻醉時血流動力學及恢復之比較研究. Acta Anaesthesiologica Sinica, 36(1), 31-36. https://www.airitilibrary.com/Article/Detail?DocID=P20170519003-199803-201904170006-201904170006-31-36
- 蘇修儀（2009）。運用多尺度熵於植入式中央靜脈輸液管Port-A病患之麻醉術後身體平衡能力恢復之研究〔碩士論文，元智大學〕。華藝線上圖書館。https://doi.org/10.6838/YZU.2009.00087