- 期刊
Kikuchi-Fujimoto Disease: A Case Report
菊池-藤本氏病(Kikuchi-Fujimoto)－病例報告
摘要
本文報告一例罕見之典型壞死性組織球性淋巴節炎，又稱為菊池－藤本氏病（Kikuchi-Fujimoto氏病）。患者為１５歲女性於右頸部發生二處皮下腫瘤，大腫瘤切除後顯示為壞死性組織球性淋巴節炎。經及時給予非類固醇抗發炎劑後，小腫瘤在１個月內消失，追蹤６個月內未有復發現象。Kikuchi-Fujimoto氏病是一自限性、壞死性組織球淋巴節炎，必須和惡性淋巴瘤區分。任何淋巴節切片在病理下若有破碎的細胞核、壞死、組織球增生而沒有明顯的中性白血球浸潤時，則需考慮Kikuchi-Fujimoto氏病，特別是在年輕女性患者合併頸部淋巴腫大時。
並列摘要
We describe a rare but typical case of Kikuchi-Fujimoto disease (KFD) .Two subcutaneous nodules appeared suddenly on the right of the neck of a 15-year-old girl. Microscopy of a surgical specimen of the larger nodule showed necrotizing lymphadenitis. Prompt treatment with mepirizole resulted in the disappearance of the smaller nodule. No recurrence was noted during 6 months of follow-up .KFD is a rare, self-limiting , necrotizing histiocytic lymphadenitis that needs to be differentiated from malignant lymphoma. Any nodal biopsy showing fragmented nuclei, necrosis, and karyorrhexis without prominent neutrophils should alert the physician to consideration of KFD, especially in a young woman presenting with cervical lymphadenopathy.
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