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Encapsulated Columnar-Cell Carcinoma of the Thyroid: A Case Report

甲狀腺高柱狀細胞上皮癌-病例報告

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摘要


高柱狀細胞上皮癌為一罕見的甲狀腺乳突上皮癌亞型,其組識學及免疫組識學的特徵和典型的甲狀腺乳突上皮癌不盡相同。由於它生長快速、容易再發以及遠處轉移,所以被世界衛生組識指為甲狀腺乳突上皮癌的侵略型變異。本篇報告一位發生在25歲女性的甲狀腺高柱狀細胞上皮癌,並回顧文獻並討論其組識病理特徵、鑑別診斷、以及預後因子。

並列摘要


Columnar-cell carcinoma is a rare form of papillary thyroid carcinoma. It is a biologically aggressive variant, according to the World Health Organization classification, due to its rapid growth, high local recurrence rate, and frequent lung, brain, and bone metastases. However, recent reports indicate encapsulated tumors confined to the thyroid gland are associated with a more favorable prognosis. We report a case of encapsulated columnar-cell carcinoma occurring in the right lobe of the thyroid in a 25-year-old female and discuss the histopathologic features, differential diagnosis, and prognostic factors.

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