- 期刊
Elevation of Intraocular Pressure after Intravitreal Injection of Triamcinolone Acetonide in Taiwanese Patients
台灣人接受玻璃體內注射康寧克通A之後的眼壓上升情形
摘要
本篇研究目的在探討病人接受玻璃體內注射康寧克通A之後發生眼壓上升的比例以及時問點。回顧性的探討包括52位病人，所有的病人都接受單次玻璃體內注射4毫克的康寧克通A。有意義的眼壓上升定義為術後的眼壓高於21毫米汞柱。本研究包含了26位男性以及26位女性。平均年齡為59.4歲，術前的平均眼壓以及術後的平均最高眼壓分別為14.6毫米汞柱以及21.5毫米汞柱。當中有19位病人(36.5%)在術後平均26天後發生了有意義的眼壓上升。而19位病人當中有17位的眼壓可以用局部青光眼藥物得到有效的控制。不論術後是否發生了有意義的眼壓上升，在玻璃體內注射4毫克的康寧克通A術後發生眼壓上升的情形是很常見的，這個現象通常發生在術後一個月左右。因此對於考慮接受這項治療的病人應該充分被告知這項副作用。
並列摘要
The purpose of this study was to investigate the incidence and timing of elevation in intraocular pressure (IOP) after intravitreal injection of triamcinolone acetonide (IVTA). This was a retrospective observational case series that included 52 eyes from 52 patients. All patients received intravitreal injection with 4 mg of triamcinolone acetonide. Significant IOP elevation was defined as pressure greater than 21 mmHg. There were 26 males and 26 females included in this study. The mean age was 59.4 years. The mean IOP at baseline and postoperative mean highest IOP were 14.6 mmHg and 21.5 mmHg, respectively. There were 19 (36.5%) patients who experienced significant IOP elevation at a mean of 26.0 days after IVTA. IOP was well-controlled by topical antiglaucoma medication in 17 of these 19 patients. IOP elevation after intravitreal injection with 4 mg of triamcinolone acetonide is not a rare finding. This phenomenon usually starts approximately 1 month after IVTA. Patients considering this treatment should be fully informed of this known adverse effect.