In this paper, we report the caring for a patient with bipolar disorder who was in a depressed episode after experiencing spouse's death during his admission to the acute ward. Using Neuman systems Model to assess the patient's physical, psychological, sociocultural, developmental, and spiritual perspectives of health, we found that this patient had such problems as high risk of suicide, sleep pattern disturbance, lack of individual coping ability, change of family dynamic processes, and disabi1ity in social interaction. In addition to taking care of these manifested problems proper1y, we also applied crisis intervention to help the patient deal with the grief of spouse's death, the burden of rearing children, and the stress of financial debt. Nursing staff, in taking care of this patient, realized that utilization of all avai1able resources are mandatory in assisting c1ients out of the crisis so as to provide a holistic mind-body-cultural care and promote health and achieve great satisfaction in doing the job.