- 期刊
Effects of Flumazenil on Fishers Martes pennanti Restrained with tiletamine-zolazepam
並列摘要
As part of a project to restore the fisher Martes pennanti in Pennsylvania, USA, we evaluated flumazenil (0.02 mg/kg) for partial reversal of tiletamine-zolazepam (10.0-11.0 mg/kg; i.e. antagonizing the effects of zolazepam) by monitoring immobilization intervals and physiologic responses of fishers (N = 4). Flumazenil reduced mean down time and alert time, but did not reduce mean recovery time. Trends in respiratory rate, body temperature, pulse rate and arterial oxygen saturation expressed by immobilized fishers were not altered by flumazenil within eight minutes post-injection. Flumazenil did not enhance practical utility of tiletamine-zolazepam at 10.0-11.0 mg/kg because fishers that received flumazenil exhibited residual tiletamine effects such as prolonged recovery and profound ataxia.
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