- 期刊
Screening for nutritional risk in hospitalized children with liver disease
摘要
Background and Objectives: Malnutrition is a major contributor to morbidity and mortality from pediatric liver disease. We investigated the prevalence of both malnutrition and high nutritional risk in hospitalized children with liver disease as well as the rate of in-hospital nutritional support. Methods and Study Design: A total of 2,874 hospitalized children and adolescents with liver disease aged 1 to 17 years (inclusive) were enrolled. Malnutrition was screened by anthropometric measures (height-for-age, weight-for-height, weight-for-age, and BMI-for- age z-scores). The Screening Tool for Risk on Nutritional Status and Growth (STRONGkids) was used to evaluate nutritional risk status. Nutrition markers in blood, rate of nutritional support, length of hospital stay, and hospital fees were compared among nutritional risk groups. Results: The overall prevalence of malnutrition was 38.6%. About 20.0% of children had high nutritional risk, and prevalence of malnutrition was markedly greater in the high nutritional risk group compared with the moderate risk group (67.9% vs 31.3%). Serum albumin and prealbumin differed significantly between high and moderate risk groups (p＜0.001). Only 8.9% of children with high nutritional risk and 3.5% with moderate nutritional risk received nutrition support during hospitalization. Children with high nutritional risk had longer hospital stays and greater hospital costs (p＜0.001). Conclusions: The prevalence of malnutrition is high in children with liver disease. High nutritional risk is also prevalent at admission. Albumin and prealbumin are sensitive markers for distinguishing nutritional risk groups. High nutritional risk prolongs length of stay and increases hospital costs. The nutritional support rate is still low and requires standardization.
延伸閱讀
- 林明燦、曹龍彥、沈銘鏡（1994）。Liver Function in Patients with Vitamin K Deficiency in Infancy。Acta Paediatrica Sinica，35(6)，514-521。https://doi.org/10.7097/APS.199412.0514
- Candido, H. L., Fonseca, E. A. D., Feier, F. H., Pugliese, R., Benavides, M. A., Silva, E. D., Gordon, K., Abreu, M. G. D., Canet, J., Chapchap, P., & Neto, J. S. (2015). Risk Factors Associated with Increased Morbidity in Living Liver Donation. Journal of Transplantation, 2015(), 105-112. https://doi.org/10.1155/2015/949674
- Lu, L., Mao, X., Sheng, J., Huang, J., Wang, Y., Tang, Q., & Cai, W. (2013). Development and validation of a pediatric nutritional screening score (PNSS) for hospitalized children. Asia Pacific Journal of Clinical Nutrition, (), 1-16. https://doi.org/10.6133/apjcn.032017.17
- Widodo, A. D., Soelaeman, E. J., Dwinanda, N., Narendraswari, P. P., & Purnomo, B. (2017). Chronic liver disease is a risk factor for malnutrition and growth retardation in children. Asia Pacific Journal of Clinical Nutrition, 26(S1), s57-s60. https://doi.org/10.6133/apjcn.062017.s10
- 王雅芳、賴苡汝、李宜臻、黃鈺婷（2017）。Nutrition screening of hospitalized patients with cancer using MNA and MUST。大仁學報，(51)，41-53。https://www.airitilibrary.com/Article/Detail?DocID=P20101109004-201709-201801240006-201801240006-41-53