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鰻骨粉與碳酸鈣為鈣源對老鼠鈣利用效果之比較

Comparison of Eel Bone Powder and Calcium Carbonate on Calcium Bioavailability in Rats

摘要


Recently, Taiwan has become an aging society. Preventing osteoporosis is getting more attention. Although many kinds of calcium compounds are available commercially, the active or bioavailable compounds which would contribute to the prevention of osteoporosis have not been determined. The bioavailability of calcium carbonate (C) and eel bone powder (E) as dietary calcium sources was compared in this study. Male Wistar rats (50g BW) were fed ad libitum on diets with a low (L, 0.15%), moderate (N, 0.53%), and high (H, 1.0%) calcium levels for four weeks. Distilled water was supplied instead of tap water. The results show that absorption in the eel bone powder group was 96.6±1.7% in the low Ca diet; 43.5±5.8% in the moderate Ca diet; and 11.1±3.0% in the high Ca diet; respectively. There is no significant difference in absorption compared with the control group. However, the absorption of calcium in both calcium sources was decreased when the diet contained increasing calcium amount, especially being significantly lower in the high Ca diet (p<0.05). The weight and calcium content of femur were significantly low in the low Ca diet (p<0.05) but did not increase from high Ca diet in either calcium sources. Also there was no significant difference between calcium sources. The effect of high calcium diet on the weight and calcium retention of kidney were also investigated. We found the calcium content (6.62±1.13 mg/kidney) of kidney in the HC group was significantly higher than HE (3.02±2.20 mg/kidney) group (p<0.05).

並列摘要


Recently, Taiwan has become an aging society. Preventing osteoporosis is getting more attention. Although many kinds of calcium compounds are available commercially, the active or bioavailable compounds which would contribute to the prevention of osteoporosis have not been determined. The bioavailability of calcium carbonate (C) and eel bone powder (E) as dietary calcium sources was compared in this study. Male Wistar rats (50g BW) were fed ad libitum on diets with a low (L, 0.15%), moderate (N, 0.53%), and high (H, 1.0%) calcium levels for four weeks. Distilled water was supplied instead of tap water. The results show that absorption in the eel bone powder group was 96.6±1.7% in the low Ca diet; 43.5±5.8% in the moderate Ca diet; and 11.1±3.0% in the high Ca diet; respectively. There is no significant difference in absorption compared with the control group. However, the absorption of calcium in both calcium sources was decreased when the diet contained increasing calcium amount, especially being significantly lower in the high Ca diet (p<0.05). The weight and calcium content of femur were significantly low in the low Ca diet (p<0.05) but did not increase from high Ca diet in either calcium sources. Also there was no significant difference between calcium sources. The effect of high calcium diet on the weight and calcium retention of kidney were also investigated. We found the calcium content (6.62±1.13 mg/kidney) of kidney in the HC group was significantly higher than HE (3.02±2.20 mg/kidney) group (p<0.05).

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