透過您的圖書館登入
IP:54.160.245.243
  • 期刊
  • OpenAccess

糙薏仁對致敏鼠過敏反應之影響

Effect of Dehulled Adlay on Allergic Responses of Sensitized Mice

摘要


To investigate the effect of dietary dehulled adlay on allergic responses of sensitized animals, BALB/c mice aged six weeks were fed three different diets containing 0% (control group), 20% and 90% dehulled adlay, respectively. After six weeks’ feeding period, the mice were sensitized twice by intraperitoneal injection of ovalbumin and aluminum hydroxide, and then sacrificed two weeks later. During the feeding period, the apparent change of the mice, the body weight change and total feed intake were recorded. The mice were bled retroorbitally for serum ovalbumin-specific IgE and IgG(subscript 2a) antibodies determination. The results showed that there were no significant differences in the body weight, total feed intake and the relative tissue weight (except lung) of the mice (P>0.05) among the three groups. Significantly lower serum anti-OVA IgE level and higher IgG(subscript 2a) level (P<0.05) were noted in the 20% adlay group compared to those of the control group. Significantly higher serum anti-OVA IgE level was noted in the 90% adlay group compared to those of the control group. However, there was no significant difference in the serum anti-OVA IgG(subscript 2a) between the 90% adlay group and control group. In addition, the apparent change of mice was noted in the 90% adlay group. The hair became more yellowish, less lustrous and smoothless. The significantly lower serum anti-OVA IgE and higher IgG(subscript 2a) antibody productions in the OVA-sensitized mice fed 20% adlay diet suggesting that 20% adlay group might improve allergic effect, but not the 90% adlay diet.

關鍵字

糙薏仁 免疫球蛋白 過敏

並列摘要


To investigate the effect of dietary dehulled adlay on allergic responses of sensitized animals, BALB/c mice aged six weeks were fed three different diets containing 0% (control group), 20% and 90% dehulled adlay, respectively. After six weeks’ feeding period, the mice were sensitized twice by intraperitoneal injection of ovalbumin and aluminum hydroxide, and then sacrificed two weeks later. During the feeding period, the apparent change of the mice, the body weight change and total feed intake were recorded. The mice were bled retroorbitally for serum ovalbumin-specific IgE and IgG(subscript 2a) antibodies determination. The results showed that there were no significant differences in the body weight, total feed intake and the relative tissue weight (except lung) of the mice (P>0.05) among the three groups. Significantly lower serum anti-OVA IgE level and higher IgG(subscript 2a) level (P<0.05) were noted in the 20% adlay group compared to those of the control group. Significantly higher serum anti-OVA IgE level was noted in the 90% adlay group compared to those of the control group. However, there was no significant difference in the serum anti-OVA IgG(subscript 2a) between the 90% adlay group and control group. In addition, the apparent change of mice was noted in the 90% adlay group. The hair became more yellowish, less lustrous and smoothless. The significantly lower serum anti-OVA IgE and higher IgG(subscript 2a) antibody productions in the OVA-sensitized mice fed 20% adlay diet suggesting that 20% adlay group might improve allergic effect, but not the 90% adlay diet.

並列關鍵字

dehulled adlay immunoglobulin allergy

被引用紀錄


陳信榮(2014)。光質對水耕栽培薏苡芽菜抗氧化活性之影響〔碩士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU.2014.01494
鍾成沛(2011)。薏仁麩皮乙醇萃取物之活性篩選及其乙酸乙酯區分層之化學組成研究〔博士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU.2011.10497
陳宏彰(2010)。薏仁麩皮調節過敏免疫反應之研究及其活性成分之分離與鑑定〔博士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU.2010.00077
林慧青(2007)。餵食小米及薏仁加工產品在緊迫動物模式下對胃黏膜損傷與腸道酵素活性及血清鈣濃度之影響〔碩士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU.2007.02613
夏詩閔(2006)。薏苡麩皮及薏苡殼甲醇萃取物對大鼠卵巢顆粒細胞分泌孕酮之效應〔博士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU.2006.01185

延伸閱讀