- 期刊
- OpenAccess
Variability of Histologic Pattern in Recurrent Soft Tissue Sarcoma Originally Diagnosed as Liposarcoma
異型新生之後腹腔脂肪肉瘤
並列摘要
The clinicopathologic significance and histopathologic classification of liposarcoma are well delineated in previous studies, but the literature on recurrent dediffenentiated liposarcoma is rare. We described a case of recurrent dedifferentiated retroperitoneal liposarcoma with light microscopy features of rhabdomyosarcoma. This loss of one cell-specific marker and gain of another is termed the ”antigenic shift” phenomenon and appeared to foretell the emergence of a true second phenotype. The literature on dedifferentiated liposarcoma is reviewed, and the significance of this case in terms of a current model of mesenchymal differentiation is discussed, with particular attention to the postulate of a common precursor for a variety of soft-tissue tumor histologies.
延伸閱讀
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