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藥物動力學在臨床上之應用:藥物動力學服務

Pharmacokinetics in Clinical Practice: Pharmacokinetic Service

摘要


藥物動力學服務是利用藥物於血中濃度,藥物動力學及藥物藥效學原理,以期提供個人臨床上最佳設計的藥物治療。本文中針對此就學理、臨床應用、臨床決策及其應用限制做詳細報導。目標是提供藥物動力學服務全面性,且以病人為主的應用介紹:包括如何利用藥物於血中濃度監測的結果提供臨床建議,哪些藥必須監測,及藥物治療監測的報告標準結構及特性。

並列摘要


Pharmacokinetic service is about using drug serum concentrations, Pharmacokinetics, and pharmacodynamics to individualize and optimize patient response to drug therapy. It is also about understanding the merits, limitations and applications of using serum drug concentrations in quantitative decision making. The aims of this paper are that covers in detail the commonly monitored using serum drug concentrations as adjuncts to decision making, how drugs are monitored, and the template for characterizing outcomes of TDM from both system-related and patient-centered viewpoints.

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