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Extra-gastrointestinal Stromal Tumor: Report of Two Cases

腸胃道外間質細胞瘤:二病例報告

摘要


腸胃道間質細胞瘤通常起源於腸胃道,它的診斷需靠免疫組織染色來確定;源自於腸胃道外的間質細胞瘤我們稱之爲腸胃道外間質細胞瘤,是一非常少見的腫瘤。在過去六年中,我們有兩個病人被診斷爲腸胃道外間質細胞瘤,一位男性、一位女性,都以一可觸摸到的腹部腫瘤爲表徵;其中一位病人接受胰頭十二指腸切除術,另一位病人接受腹內腫瘤切除術,兩個病人至今仍存活。我們分析119個病人發現女性有較高的發生率,且大部分的腫瘤沒有症狀,所以都是在體積比較大時才被診斷。手術切除仍是治療腸胃道外間質細胞瘤最好的方法。

關鍵字

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並列摘要


Gastrointestinal stromal tumors (GIST) usually originate from the gastrointestinal wall. GISTs not originating from the gastrointestinal tract, named extragastrointestinal stromal tumors (EGIST) are very rare. This study aims to find the characteristics of EGIST by reviewing the literature. In the past 6 years, we have treated 2 patients with EGIST. One was a 49-year-old man and the other, a 72-yearoldwoman. Both of them presented with a large palpable abdominal mass. One patient underwent a pancreaticoduodenectomy because the tumor was located near the duodenum; the other received resection of the tumor without the need for resection of the gastrointestinal tract. We searched on PubMed and reviewed 119published cases of EGIST, including the two patients treated by us, in the related English literature from 1953 to March 2007. Both of our patients survived postoperatively and are still living well, of one survival already exceeding 5 years. Based on the reviewed studies, the incidence of EGIST is slightly higher in women. Owing to a leak of symptoms in the beginning period, the EGIST can reach a relatively large size. Curative resection is at present the main option for EGIST.

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