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Options for Treatment of Chronic Intractable Low Back Pain: A Controlled Randomized Clinical Trial between Pulsed Radiofrequency Stimulation and Topical Steroid Injection of the L2 Intervertebral Foramen Nerve Root

頑固性下背痛的治療選擇:第二腰神經根脈衝式高頻熱凝刺激與局部類固醇治療的隨機臨床試驗分析

摘要


對於頑固性下背痛的病人,利用脈衝式高頻熱凝刺激第二腰神經根的治療方式,一直缺乏實證。我們的研究計劃針對下背痛超過三個月的病人,隨機分組成治療組及對照組,治療組給予第二腰神經根脈衝式高頻熱凝刺激,對照組給予第二腰神經根局部類固醇治療。總共收錄二十五位病人,其中二十四位完成分組及治療,二十二位完成六個月的問卷追蹤,包括歐氏下背痛失能程度量表、疼痛指數評估、羅蘭-摩理斯生活障礙問卷,及SF-36生活品質問卷。研究結果顯示在歐氏下背痛失能程度量表及羅蘭-摩理斯生活障礙問卷,兩組在治療後六個月都有顯著改善,但兩組間沒有差異。我們的結論是針對頑固性下背痛的病人,利用脈衝式高頻熱凝刺激第二腰神經根與第二腰神經根局部類固醇治療的效果相似。

關鍵字

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並列摘要


Objective: A comparison of the effects of pulsed radiofrequency stimulation and topical steroid injection of the L2 intervertebral foramen nerve root for chronic intractable low back pain was made in a prospective, randomized, double blind controlled trial. Methods: Twenty-five screened out of 81 patients entered the study. One was excluded just before the intervention and 2 were lost to follow-up. In one group of patients (N=11, group Ⅰ) pulsed radiofrequency was used and in the other group (N=11, group Ⅱ) only a topical steroid was given. The visual analog scale (VAS), Oswestry disability index (ODI), Roland-Morris disability questionnaire (RMDQ), and Short-Form 36 (SF-36) questionnaire were used to measure the treatment effects. Results: Six months after treatment a significant reduction in ODI and RMDQ scores was demonstrated in both groups, but there was no significant difference between the two groups. The quality of life scales showed a positive trend in both groups in the SF-36 domain physical functioning, bodily pain, role emotional and mental health, but significance was reached only in the domain bodily pain at 6 months in group I. Conclusions: This study suggests that for chronic intractable low back pain, treatment with PRF stimulation of the L2 intervertebral foramen nerve root is equally effective in comparison with treatment of intervertebral foramen nerve root steroid injection.

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