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Pigmented Villonodular Synovitis: Report of Twelve Cases and Review of the Literature

並列摘要


Twelve patients with the diagnosis of pigmented villonodular synovitis (PVNS) were retrospectively reviewed. There were 4 males and 8 females. Ages ranged from 21 to 74 years, with an average of 39.7 years. The location of the lesions was knee in 7, hip in 2, ankle in 2 and one rare case involving the elbow. The clinical presentation included joint swelling, pain, limited range of motion, and ulnar and radial palsy which was noted in the patient with a huge elbow mass. Preoperatively abnormal radiographic changes including soft tissue swelling, bone erosion and osteolytic lesion, were found in 5 patients. According to Enneking’s classification of soft tissue tumor, the patients were subgrouped into stage Ⅰ, nodular lesion, in 3 patients; stage Ⅱ, diffuse lesion, in 5 patients; stage Ш, extracapsular extension with neoplastic like lesion, in 4 patients. The choice of treatment according to this classification was as follows: stage Ⅰ, simple excision; stage Ⅱ, total synovectomy; stage Ш, total synovectomy with bone curettage or prosthetic replacement if necessary. One patient had a recurrent ankle mass 4 years after simple excision; another excision, curettage and distal tibia-fibula fusion was performed. Other complications included limited range of motion of knee in one, and early osteoarthritic change of knee in one patient. The average follow-up necessary.

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