台灣地區脂肪攝取量與女性乳癌及結直腸癌死亡率的生態相關研究

An Ecological Study of dietary Fat intake and Mortality Rates from Breast Cancer and Colorectal Cancer in Taiwanese Women

陳科榕(Ko-Jung Chen) ； 廖勇柏(Yung-Po Liaw)

《中華民國營養學會雜誌》 27卷4期 (2002/12) Pp. 202-210

https://doi.org/10.6691/JCNS.200212_27(4).0002

摘要

台灣地區女性乳癌及結直腸癌死亡率逐年上升，脂肪攝取量增加被認為是重要的危險因子。本研究利用1993~1996年國民營養調查資料庫，計算女性平均脂肪、飽和脂肪酸、及多元不飽和脂肪酸攝取量；並計算1990~1999年女性乳癌及結直腸癌直接年齡標準化死亡率值(Age-adjusted Standardized Mortality Rate, ASR), 使用皮爾森相關(Pearson correlation)進一步分析脂肪攝取量與女性乳癌及結直腸癌死亡率之相關性。研究結果顯示台灣鄉鎮按國民營養資料庫所分層之女性乳癌及結直腸癌死亡率有相似的地理分布(r = 0.91， P = 0.0045)。脂肪與女性乳癌(r = 0.218， p = 0.62)及與結直腸癌(r =0.265， p=0.57)均呈正相關，但未達統計顯著意義。飽和脂肪酸與女性乳癌(r = 0.482 p=0.27)及與結直腸癌(r = 0.465 P = 0 . 29)亦呈正相關，也未達統計顯著性。相反地，多元不飽和脂肪酸與女性乳癌(r= -0.606， P = 0.13)及與結直腸癌(r = - 0.843， P = 0.02)的均呈負相關，其中多元不飽和脂肪酸與女性結直腸癌更達統計顯著負相關。

關鍵字

脂肪攝取量 ； 乳癌 ； 結直腸癌 ； 死亡率 ； 皮爾森相關分析

並列摘要

The mortality rates for breast and colorectal cancer in women have remarkably increased recently in Taiwan, and dietary fat is considered to be an important risk factor. This study used data from the Nutrition and Health Survey in Taiwan (NAHSIT) to calculate female average intake of fat, saturated fatty acids, and polyunsaturated fatty acids. In addition, age-adjusted standardized mortality rates (ASRs) for female breast and colorectal cancer were also calculated. The Pearson correlation was used to analyze the correlation between dietary fat intake and female breast and colorectal cancer mortality rates. The results showed a similar geographical distribution between female breast and colorectal cancer mortality rates in the seven classified strata according to NAHSIT (r = 0.91, P = 0.0045). Pearson correlation analysis indicated a positive correlation between fat and both breast cancer (r = 0.218, P = 0.62) and colorectal cancer (r = 0.265, P = 0.57). However, this finding appeared to be non-significant. Saturated fatty acids Intake and both breast cancer (r = 0.482, P = 0.27) and colorectal cancer (r = 0.465, P = 0.29) also had positive correlations that
were non-significant. On the contrary, negative correlations between polyunsaturated fatty acids intake and both breast cancer (r =-0.843, P = 0.62) and colorectal cancer (r =-0.606, P = 0.62) were found. Furthermore, this negative correlation between polyunsaturated fatty acid intake and colorectal cancer was statistically significant.

並列關鍵字

dietary fat intake ； breast cancer ； colorectal cancer ； mortality ； Pearson correlation