- 期刊
- OpenAccess
Dialyzer Membrane Characteristics as an Independent Predictor of Clinical Outcomes in Hemodialysis Patients
並列摘要
BACKGROUND: Dialysis membrane is associated with differences in outcomes of long-term hemodialysis patients, thus we evaluate the correlation between the nature of dialyzers and patients' clinical outcomes.METHODS: This retrospective study examined the clinical outcomes of 179 hemodialysis patients from February 2008 to September 2010. Patients were divided into three groups according to the characteristics of the dialysis membrane. Kaplan-Meier survival curve of different categories of dialysis membrane were illustrated. The Cox proportional hazards model was employed to analyze the relative risk of different membrane groups. RESULTS: Patients dialyzed with high-flux synthetic membrane of surface area ＞ 2.0 m^2 were significantly younger, had higher levels of pre-dialysis creatinine and BMI compared with those of the other two groups. Better results of cumulative survival by Kaplan-Meier analysis were shown. There was 51% risk reduction for death in the high-flux with smaller surface group and 94% risk reduction for death in the high-flux with larger surface group. Membrane characteristics, albumin and hsCRP remained the only significant factors associated with survival in multivariate Cox regression analysis. CONCLUSION: Our data revealed that high-flux synthetic membrane with larger surface area had significant benefits of prolonging survival, good nutritional status and less inflammation for longterm hemodialysis patients. (Acta Nephrologica 2011; 25: 105-112)
延伸閱讀
- Zeng, Y., Xu, Y., Zhang, B., Xu, C., Cao, J., Deng, Q., Li, S., Yi, T., & Qi, A. (2022). Clinical prognostic role of bioimpedance phase angle in diabetic and non-diabetic hemodialysis patients. Asia Pacific Journal of Clinical Nutrition, 31(4), 619-625. https://doi.org/10.6133/apjcn.202212_31(4).0005
- Zeng, Y., Xu, Y., Zhang, B., CaiXu, Cao, J., QianDeng, Li, S., Yi, T., & Qi, A. (2013). Clinical prognostic role of bioimpedance phase angle in diabetic and non-diabetic hemodialysis patients. Asia Pacific Journal of Clinical Nutrition, (), 1-14. https://doi.org/10.6133/apjcn.202209/PP.0005
- 江銘彥、呂宜樺、黃志強（2017）。Association of Sub-Clinical Inflammation Status and Peritonitis Development in Peritoneal Dialysis Patients。腎臟與透析，29(2)，72-75。https://doi.org/10.6340/KD.2017.29(2).05
- Chang, B. Y., Mau, L. W., Hwang, S. J., Hwang, S. J., Chien, L. C., Hwang, L. L., & Tsai, C. Y. (2000). Evaluation of Quality of Life on Dialysis: A Comparison between Hemodialysis and Peritoneal Dialysis Patients. Acta Nephrologica, 14(4), 307-307. https://www.airitilibrary.com/Article/Detail?DocID=10131671-200010-14-4-307-307-o
- Lin, M. H., Chang, C. H., Yen, C. L., Fan, P. C., Tu, K. H., Hsu, H. H., Tian, Y. C., & Lee, C. C. (2022). Outcomes of Elderly Hemodialysis Patients Who Have Survived Infection-Related Hospitalization: A Nationwide Cohort Study. Acta Nephrologica, 36(1), 39-48. https://doi.org/10.6221/AN.202203_36(1).0006