Forced Vital Capacity and Chest Excursion in Children with Duchenne Muscular Dystrophy

裘馨氏肌肉萎縮症病童肺活量及胸腔活動度

蔡美文(Mei-Wen Tsai) ； 陳秋芬(Chue-Fun Chen)

《中華民國物理治療學會雜誌》 13卷 (1988/09) Pp. 1-7

https://doi.org/10.29616/JPTAROC.198809.0001

摘要

The purpose of this study was to investigate the involvement of respiratory muscle and lung volume in children with Duchenne muscular dystrophy. The index of respiratory muscle weakness and lung volume included forced vital capacity, the ratio of forced expiratory volume in 1 second and forced vital capacity, and chest excursion. Sixteen boys with Duchenne muscular dystrophy (age ranged from 6 to 13 years old) and thirty-three healthy school boys with matched age, body height and weight were included in this study. All subjects were asked to take their maximal inspiration and then exhale fully in the tests. Forced vital capacity and forced expiratory volume in 1 second were measured with spirometer in supine and sitting position. The chest excursion was measured the changes of rib circumference with a plastic centimeter tape at the level of xiphoid process. Our findings confirmed that children with Duchenne muscular dystrophy had lower forced vital capacity (l.4±0.3ℓ), % predicted forced vital capacity (78.4±16.8%) than normal controls. However, the ratio of forced expiratory volume in 1 second and forced vital capacity in children with Duchenne muscular dystrophy (93.5±7.3%) were similar to normal controls. Therefore, there was lung volume restriction in children with Duchenne muscular dystrophy. The chest excursion at the level of xiphoid process was significantly smaller in children with Duchenne muscular dystrophy (2.5+1.6cm). This might be the effects of alternation in the elastic properties of the lungs and chest wall due to respiratory muscles weakness. Differences in vital capacity between the upright and supine postures were small, it represented the relative preservation of diaphragm function in DMD.

並列摘要

The purpose of this study was to investigate the involvement of respiratory muscle and lung volume in children with Duchenne muscular dystrophy. The index of respiratory muscle weakness and lung volume included forced vital capacity, the ratio of forced expiratory volume in 1 second and forced vital capacity, and chest excursion. Sixteen boys with Duchenne muscular dystrophy (age ranged from 6 to 13 years old) and thirty-three healthy school boys with matched age, body height and weight were included in this study. All subjects were asked to take their maximal inspiration and then exhale fully in the tests. Forced vital capacity and forced expiratory volume in 1 second were measured with spirometer in supine and sitting position. The chest excursion was measured the changes of rib circumference with a plastic centimeter tape at the level of xiphoid process. Our findings confirmed that children with Duchenne muscular dystrophy had lower forced vital capacity (l.4±0.3ℓ), % predicted forced vital capacity (78.4±16.8%) than normal controls. However, the ratio of forced expiratory volume in 1 second and forced vital capacity in children with Duchenne muscular dystrophy (93.5±7.3%) were similar to normal controls. Therefore, there was lung volume restriction in children with Duchenne muscular dystrophy. The chest excursion at the level of xiphoid process was significantly smaller in children with Duchenne muscular dystrophy (2.5+1.6cm). This might be the effects of alternation in the elastic properties of the lungs and chest wall due to respiratory muscles weakness. Differences in vital capacity between the upright and supine postures were small, it represented the relative preservation of diaphragm function in DMD.

並列關鍵字

Duchenne muscular dystrophy ； Forced vital capacity ； One-second forced expiratory volume ； Chest excursion