摘要
Eosinophilic esophagitis (EoE) is a rare disorder characterized by symptoms of esophageal dysfunction and marked eosinophilic infiltration of esophageal mucosa. We present a 40-year-old male who suffered from progressive dysphagia with solid food and mild chest pain for 1 month. Upper endoscopy revealed diffuse concentric rings, longitudinal furrows and adherent white exudates. Laboratory data showed elevated total IgE but without peripheral blood eosinophilia. Histopathology of the biopsy specimen of the esophageal mucosa showed prominent intraepithelial eosinophilic infiltration (＞15/HPF). Under the diagnosis of eosinophilic esophagitis, the symptoms were non-responsive to proton pump inhibitor therapy, oral steroids were prescribed and the dysphagia improved gradually. EoE is a distinct cause of dysphagia and food impaction in adults. Our present case highlights the clinical and endoscopic features, histopathological criteria and response to medical treatment.
並列摘要
Eosinophilic esophagitis (EoE) is a rare disorder characterized by symptoms of esophageal dysfunction and marked eosinophilic infiltration of esophageal mucosa. We present a 40-year-old male who suffered from progressive dysphagia with solid food and mild chest pain for 1 month. Upper endoscopy revealed diffuse concentric rings, longitudinal furrows and adherent white exudates. Laboratory data showed elevated total IgE but without peripheral blood eosinophilia. Histopathology of the biopsy specimen of the esophageal mucosa showed prominent intraepithelial eosinophilic infiltration (＞15/HPF). Under the diagnosis of eosinophilic esophagitis, the symptoms were non-responsive to proton pump inhibitor therapy, oral steroids were prescribed and the dysphagia improved gradually. EoE is a distinct cause of dysphagia and food impaction in adults. Our present case highlights the clinical and endoscopic features, histopathological criteria and response to medical treatment.
延伸閱讀
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